Literature DB >> 1172955

Hypertensive crisis and death associated with phencyclidine poisoning.

J W Eastman, S N Cohen.   

Abstract

Phencyclidine hydrochloride is a dangerous drug. Its incidence as the causative agent in childhood poisoning is increasing. A pressor effect of phencyclidine has been noted in studies both in man and in experimental animals. We summarize seven cases of poisoning with this drug, including one in which death occurred following a hypertensive crisis. Patients who have ingested this drug should have continuous monitoring of blood pressure in an intensive care unit.

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Year:  1975        PMID: 1172955

Source DB:  PubMed          Journal:  JAMA        ISSN: 0098-7484            Impact factor:   56.272


  4 in total

Review 1.  Street drug abuse leading to critical illness.

Authors:  Babak Mokhlesi; Prasad S Garimella; Aaron Joffe; Valerie Velho
Journal:  Intensive Care Med       Date:  2004-03-04       Impact factor: 17.440

2.  First dose behavioral tolerance to phencyclidine on food-rewarded bar pressing behavior in the rat.

Authors:  D M Ruffing; E F Domino
Journal:  Psychopharmacology (Berl)       Date:  1980       Impact factor: 4.530

3.  Phencyclidine--states of acute intoxication and fatalities.

Authors:  R S Burns; S E Lerner; R Corrado; S H James; S H Schnoll
Journal:  West J Med       Date:  1975-11

4.  Whole body autoradiography of 3H-phencyclidine in mice.

Authors:  A Chari-Bitron; G A Simon; T Kadar; L Motola
Journal:  Arch Toxicol       Date:  1979-12       Impact factor: 5.153

  4 in total

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