Literature DB >> 11728874

What determines nasal carriage of Staphylococcus aureus?

S J Peacock1, I de Silva, F D Lowy.   

Abstract

Nasal carriage of Staphylococcus aureus is an important risk factor for infection by this organism in both community and hospital settings; this article reviews the role of host and bacterial factors in carriage. A host genetic influence appears likely but the phenotypic determinants are unknown. Possibilities include variability in host adhesins, immune response or secretion of antimicrobial molecules. Colonization resistance by S. aureus, together with the observation that persistent carriers often carry a single strain whereas intermittent carriers can be colonized with unrelated strains over time, suggests that bacterial factors could also be involved.

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Year:  2001        PMID： 11728874     DOI： 10.1016/s0966-842x(01)02254-5

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN： 0966-842X            Impact factor:   17.079


  120 in total

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