Literature DB >> 11728829

Mechanisms involved in alpha6beta1-integrin-mediated Ca(2+) signalling.

H Schöttelndreier1, B V Potter, G W Mayr, A H Guse.   

Abstract

Contact of Jurkat T-lymphocytes with the extracellular matrix (ECM) protein laminin resulted in long-lasting alpha6beta1-integrin-mediated Ca(2+) signalling. Both Ca(2+) release from thapsigargin-sensitive Ca(2+) stores and capacitative Ca(2+) entry via Ca(2+) channels sensitive to SKF 96365 constitute important parts of this process. Inhibition of alpha6beta1-integrin-mediated Ca(2+) signalling by (1) the src kinase inhibitor PP2, (2) the PLC inhibitor U73122, and (3) the cyclic adenosine diphosphoribose (cADPR) antagonist 7-deaza-8-Br-cADPR indicate the involvement of src tyrosine kinases and the Ca(2+)-releasing second messengers D-myo-inositol 1,4,5-trisphosphate (InsP3) and cADPR.

Entities:  

Mesh：

Substances：

Year:  2001        PMID： 11728829     DOI： 10.1016/s0898-6568(01)00225-x

Source DB:  PubMed          Journal:  Cell Signal        ISSN： 0898-6568            Impact factor:   4.315


  9 in total

1.  Cellular effects and metabolic stability of N1-cyclic inosine diphosphoribose and its derivatives.

Authors:  T Kirchberger; G Wagner; J Xu; C Cordiglieri; P Wang; A Gasser; R Fliegert; S Bruhn; A Flügel; F E Lund; L-H Zhang; B V L Potter; A H Guse
Journal:  Br J Pharmacol       Date:  2006-09-11       Impact factor: 8.739

2.  Integrin regulation of cytoplasmic calcium in excitatory neurons depends upon glutamate receptors and release from intracellular stores.

Authors:  C-Y Lin; L G W Hilgenberg; M A Smith; G Lynch; C M Gall
Journal:  Mol Cell Neurosci       Date:  2008-01-17       Impact factor: 4.314

3.  Thrombospondin-1 and angiotensin II inhibit soluble guanylyl cyclase through an increase in intracellular calcium concentration.

Authors:  Saumya Ramanathan; Stacy Mazzalupo; Scott Boitano; William R Montfort
Journal:  Biochemistry       Date:  2011-08-16       Impact factor: 3.162

4.  MCP-1-activated monocytes induce apoptosis in human retinal pigment epithelium.

Authors:  Dongli Yang; Susan G Elner; Xun Chen; Matthew G Field; Howard R Petty; Victor M Elner
Journal:  Invest Ophthalmol Vis Sci       Date:  2011-07-29       Impact factor: 4.799

5.  Trophoblast adhesion of the peri-implantation mouse blastocyst is regulated by integrin signaling that targets phospholipase C.

Authors:  Jun Wang; Linda Mayernik; D Randall Armant
Journal:  Dev Biol       Date:  2006-09-14       Impact factor: 3.582

6.  Laminin interactions with head and neck cancer cells under low fluid shear conditions lead to integrin activation and binding.

Authors:  Susan M Fennewald; Carla Kantara; Sarita K Sastry; Vicente A Resto
Journal:  J Biol Chem       Date:  2012-04-30       Impact factor: 5.157

7.  FM-test: a fuzzy-set-theory-based approach to differential gene expression data analysis.

Authors:  Lily R Liang; Shiyong Lu; Xuena Wang; Yi Lu; Vinay Mandal; Dorrelyn Patacsil; Deepak Kumar
Journal:  BMC Bioinformatics       Date:  2006-12-12       Impact factor: 3.169

8.  Roles of Integrins and Intracellular Molecules in the Migration and Neuritogenesis of Fetal Cortical Neurons: MEK Regulates Only the Neuritogenesis.

Authors:  Ujjwal K Rout
Journal:  Neurosci J       Date:  2013-01-20

9.  The endothelial basement membrane acts as a checkpoint for entry of pathogenic T cells into the brain.

Authors:  Xueli Zhang; Ying Wang; Jian Song; Hanna Gerwien; Omar Chuquisana; Anna Chashchina; Cornelia Denz; Lydia Sorokin
Journal:  J Exp Med       Date:  2020-07-06       Impact factor: 14.307
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.