Literature DB >> 11728330

FERMing up the synapse.

A S Shaw1.   

Abstract

The immunological synapse is characterized by the reorganization of membrane proteins at the immunological synapse. Active cytoskeletal mechanisms are involved in recruiting the TCR, accessory molecules, and the integrin LFA-1 to the contact area. Other molecules like CD43 are excluded from the contact area, but the mechanism of exclusion is unknown. Three papers in this issue of Immunity demonstrate that CD43 exclusion involves the ERM family of cytoskeletal proteins.

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Year:  2001        PMID: 11728330     DOI: 10.1016/s1074-7613(01)00237-0

Source DB:  PubMed          Journal:  Immunity        ISSN: 1074-7613            Impact factor:   31.745


  15 in total

1.  Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex.

Authors:  Keisuke Hamada; Toshiyuki Shimizu; Shigenobu Yonemura; Shoichiro Tsukita; Sachiko Tsukita; Toshio Hakoshima
Journal:  EMBO J       Date:  2003-02-03       Impact factor: 11.598

2.  Formation of microvilli and phosphorylation of ERM family proteins by CD43, a potent inhibitor for cell adhesion: cell detachment is a potential cue for ERM phosphorylation and organization of cell morphology.

Authors:  Junko Yamane; Hiroe Ohnishi; Hiroyuki Sasaki; Hisashi Narimatsu; Hajime Ohgushi; Kouichi Tachibana
Journal:  Cell Adh Migr       Date:  2011-03-01       Impact factor: 3.405

Review 3.  Age-related defects in the cytoskeleton signaling pathways of CD4 T cells.

Authors:  Gonzalo G Garcia; Richard A Miller
Journal:  Ageing Res Rev       Date:  2009-11-24       Impact factor: 10.895

4.  Age-related changes in lck-Vav signaling pathways in mouse CD4 T cells.

Authors:  Gonzalo G Garcia; Richard A Miller
Journal:  Cell Immunol       Date:  2009-06-06       Impact factor: 4.868

5.  Functional defects of SKAP-55-deficient T cells identify a regulatory role for the adaptor in LFA-1 adhesion.

Authors:  Hongyan Wang; Hebin Liu; Yuning Lu; Matt Lovatt; Bin Wei; Christopher E Rudd
Journal:  Mol Cell Biol       Date:  2007-07-23       Impact factor: 4.272

6.  Regulation of T-cell activation by phosphodiesterase 4B2 requires its dynamic redistribution during immunological synapse formation.

Authors:  Jacqueline Arp; Mark G Kirchhof; Miren L Baroja; Steven H Nazarian; Thu A Chau; Craig A Strathdee; Eric H Ball; Joaquín Madrenas
Journal:  Mol Cell Biol       Date:  2003-11       Impact factor: 4.272

7.  Asymmetric localization of flotillins/reggies in preassembled platforms confers inherent polarity to hematopoietic cells.

Authors:  Lawrence Rajendran; Madhan Masilamani; Samuel Solomon; Ritva Tikkanen; Claudia A O Stuermer; Helmut Plattner; Harald Illges
Journal:  Proc Natl Acad Sci U S A       Date:  2003-06-25       Impact factor: 12.779

8.  Phosphatidylinositol (4,5) bisphosphate controls T cell activation by regulating T cell rigidity and organization.

Authors:  Yi Sun; Radhika D Dandekar; Yuntao S Mao; Helen L Yin; Christoph Wülfing
Journal:  PLoS One       Date:  2011-11-11       Impact factor: 3.240

Review 9.  Human deafness-associated variants alter the dynamics of key molecules in hair cell stereocilia F-actin cores.

Authors:  Takushi Miyoshi; Inna A Belyantseva; Shin-Ichiro Kitajiri; Hiroki Miyajima; Shin-Ya Nishio; Shin-Ichi Usami; Bong Jik Kim; Byung Yoon Choi; Koichi Omori; Hari Shroff; Thomas B Friedman
Journal:  Hum Genet       Date:  2021-07-07       Impact factor: 4.132

10.  Regulation of lymphocyte apoptosis by interferon regulatory factor 4 (IRF-4).

Authors:  Jessica C Fanzo; Chuan-Min Hu; So Young Jang; Alessandra B Pernis
Journal:  J Exp Med       Date:  2003-02-03       Impact factor: 14.307

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