Literature DB >> 11728033

Development of live recombinant vaccine candidates against tuberculosis.

J Hess1, S H Kaufmann.   

Abstract

We report on 2 recombinant (r) live vaccine candidates that use different strategies to improve cell-mediated immunity for TB control: (i) the current TB vaccine strain Mycobacterium bovis BCG, endowed with a pore-forming cytolysin; and (ii) rSalmonella typhimurium secreting a single immunodominant antigen shared by BCG and M. tuberculosis.

Entities:  

Mesh:

Substances:

Year:  2001        PMID: 11728033     DOI: 10.1080/003655401317074473

Source DB:  PubMed          Journal:  Scand J Infect Dis        ISSN: 0036-5548


  2 in total

1.  Tuberculosis vaccines: current progress.

Authors:  Ian M Orme
Journal:  Drugs       Date:  2005       Impact factor: 9.546

2.  A second-generation anti TB vaccine is long overdue.

Authors:  Mauricio Castañón-Arreola; Yolanda López-Vidal
Journal:  Ann Clin Microbiol Antimicrob       Date:  2004-06-03       Impact factor: 3.944

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.