| Literature DB >> 11724919 |
Abstract
This review concentrates on the molecular pathology of the protein tau, including its expression in various regions of the brain. The role of post-translational modifications in fibrillogenesis is also discussed, particularly hyperphosphorylation and glycation. However, the initiating event that causes aberrant tau processing remains unclear.Entities:
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Year: 2001 PMID: 11724919 PMCID: PMC1187134
Source DB: PubMed Journal: Mol Pathol ISSN: 1366-8714