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Literature DB >> 1172370

Localization of human gene loci using spontaneous chromosome rearrangements in human-Chinese hamster somatic cell hybrids.

Abstract

Analysis of human-Chinese hamster somatic cell hybrids with spontaneously derived chromosome structural changes has provided data for the regional and subregional localization of gene loci which have previously been assigned to human chromosomes 2, 12, and X. Correlation of the expression of human gene loci with the human chromosome complements present in somatic cell hybrids indicates that the cytoplasmic malate dehydrogenase (MDH1) locus is in the 2p23yields2pter region, and red cell acid phosphatase (AcP1) is at or adjacent to 2p23. The cytoplasmic isocitrate dehydrogenase (IDH1) locus is at or adjacent to 2q11, peptidase B (Pep B) is at or adjacent to 12q21, lactate dehydrogenase B (LDH B) is in the 12q21yiedls12pter region, glucose-6-phosphate dehydrogenase (G6PD) is in the Xq24yieldsXqter region, and the gene loci for phosphoglycerate kinase (PGK), alpha-galactosidase (alpha-gal), and hypoxanthine guanine phosphoribosyltransferase (GPRT) are in the Xp21yieldsXq24 region.

Entities: Gene Species

Mesh：

Substances：

Year: 1975 PMID： 1172370 PMCID： PMC1762824

Source DB: PubMed Journal: Am J Hum Genet ISSN： 0002-9297 Impact factor: 11.025

33 in total

1. Enzyme electrophoresis on cellulose acetate gel: zymogram patterns in mgh-mouse and man--Chinese hamster somatic cell hybrids.

Authors: P Meera Khan
Journal: Arch Biochem Biophys Date: 1971-08 Impact factor: 4.013

2. Genetic analysis with human--mouse somatic cell hybrids.

Authors: M Nabholz; V Miggiano; W Bodmer
Journal: Nature Date: 1969-07-26 Impact factor: 49.962

3. Probable assignment of the locus determining human red cell acid phosphatase ACP1 to chromosome 2 using somatic cell hybrids.

Authors: S Povey; D M Swallow; M Bobrow; I Craig; V van Heyningen
Journal: Ann Hum Genet Date: 1974-07 Impact factor: 1.670

4. Characteristics of an HPRT-deficient chinese hamster cell line.

Authors: P A Gee; R T Mohandas; G R Douglas; H R Palser; B J Richardson; J L Hamerton
Journal: Cytogenet Cell Genet Date: 1974

5. The association of glucose phasphate isomerase expression with human chromosome 19 using somatic cell hybrids.

Authors: J L Hamerton; G R Douglas; P A Gee; B J Richardson
Journal: Cytogenet Cell Genet Date: 1973

6. Assignment of the genes for human peptidase A to chromosome 18 and cytoplasmic glutamic oxaloacetate transaminase to chromosome 10 using somatic-cell hybrids.

Authors: R Creagan; J Tischfield; F A McMorris; S Chen; M Hirschi; T R Chen; F Ricciuti; F H Ruddle
Journal: Cytogenet Cell Genet Date: 1973

7. Cytological mapping of human X-linked genes by use of somatic cell hybrids involving an X-autosome translocation (mouse-hamster-human X-linked markers).

Authors: K H Grzeschik; P W Allderdice; A Grzeschik; J M Opitz; O J Miller; M Siniscalco
Journal: Proc Natl Acad Sci U S A Date: 1972-01 Impact factor: 11.205

8. Genetic analysis with man-mouse somatic cell hybrids. Linkage between human lactate dehydrogenase B and peptidase B genes.

Authors: A S Santachiara; M Nabholz; V Miggiano; A J Darlington; W Bodmer
Journal: Nature Date: 1970-07-18 Impact factor: 49.962

9. Regional localization of loci for human PGM and 6PGD on human chromosome one by use of hybrids of Chinese hamster-human somatic cells.

Authors: G R Douglas; P J McAlpine; J L Hamerton
Journal: Proc Natl Acad Sci U S A Date: 1973-10 Impact factor: 11.205

10. Linkage relationships of seventeen human gene loci as determined by man--mouse somatic cell hybrids.

Authors: F H Ruddle; V M Chapman; F Ricciuti; M Murnane; R Klebe; P Meera Khan
Journal: Nat New Biol Date: 1971-07-21

11 in total

Review 1. Comparative map for mice and humans.

Authors: J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M R Kosowsky; T H Roderick
Journal: Mamm Genome Date: 1992 Impact factor: 2.957

2. The mink gene for the lambda light immunoglobulin chain: characterization of cDNA and chromosomal localization.

Authors: T M Khlebodarova; N M Matveeva; O L Serov; A M Najakshin; E S Belousov; S V Bogachev; O K Baranov
Journal: Mamm Genome Date: 1992 Impact factor: 2.957

Review 3. Comparative map for mice and humans.

Authors: J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M Kosowsky; T H Roderick
Journal: Mamm Genome Date: 1991 Impact factor: 2.957

4. [Regional localization of the genes for human IDHs, MDHs PGK, alphaGAL, G6PD by interspecific hybridization (author's transl)].

Authors: D Weil; N Van-Cong; C Finaz; R Rebourcet; C Cochet; J de Grouchy; J Frézal
Journal: Hum Genet Date: 1977-04-15 Impact factor: 4.132