| Literature DB >> 11723294 |
F C Goldstein1, A V Ashley, M Gearing, J Hanfelt, L Penix, L J Freedman, A I Levey.
Abstract
The authors examined whether the APOE-epsilon4 allele is associated with an earlier age at onset of AD in 71 African American patients with probable AD. The authors found a linear dose effect in which each copy of the epsilon4 allele was associated with a 3.6-year earlier onset of AD, indicating a dose-dependent relationship between APOE-epsilon4 and age at onset of AD in African Americans.Entities:
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Year: 2001 PMID： 11723294 DOI： 10.1212/wnl.57.10.1923
Source DB: PubMed Journal: Neurology ISSN： 0028-3878 Impact factor: 9.910