Literature DB >> 11723282

Transcallosal bands: a sign of neuronal tract degeneration in early MS?

J H Simon1, L Jacobs, R P Kinkel.   

Abstract

A pattern of injury observed in patients at high risk for MS described as transcallosal bands (TCB) is hypothesized to be the result of neuronal tract degeneration in earliest MS, extending from typical acute, focal demyelinating lesions located along the lateral borders of the corpus callosum. The TCB, a T2-hyperintense lesion traversing the corpus callosum is recognized on 3-mm thick, T2-weighted imaging, develops over months and persists over years.

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Year:  2001        PMID: 11723282     DOI: 10.1212/wnl.57.10.1888

Source DB:  PubMed          Journal:  Neurology        ISSN: 0028-3878            Impact factor:   9.910


  5 in total

Review 1.  Changes observed in multiple sclerosis using magnetic resonance imaging reflect a focal pathology distributed along axonal pathways.

Authors:  Douglas L Arnold
Journal:  J Neurol       Date:  2005-11       Impact factor: 4.849

2.  CNS inflammation and neurodegeneration.

Authors:  Tanuja Chitnis; Howard L Weiner
Journal:  J Clin Invest       Date:  2017-09-05       Impact factor: 14.808

3.  MRI of the corpus callosum in multiple sclerosis: association with disability.

Authors:  A Ozturk; S A Smith; E M Gordon-Lipkin; D M Harrison; N Shiee; D L Pham; B S Caffo; P A Calabresi; D S Reich
Journal:  Mult Scler       Date:  2010-02       Impact factor: 6.312

4.  The window of therapeutic opportunity in multiple sclerosis: evidence from monoclonal antibody therapy.

Authors:  Alasdair J Coles; Amanda Cox; Emmanuelle Le Page; Joanne Jones; S Anand Trip; Jackie Deans; Shaun Seaman; David H Miller; Geoff Hale; Herman Waldmann; D Alastair Compston
Journal:  J Neurol       Date:  2005-07-27       Impact factor: 4.849

5.  Intermittent alien hand syndrome and callosal apraxia in multiple sclerosis: implications for interhemispheric communication.

Authors:  A Lunardelli; A Sartori; P Mengotti; R I Rumiati; V Pesavento
Journal:  Behav Neurol       Date:  2014-02-18       Impact factor: 3.342

  5 in total

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