OBJECTIVE: Quetiapine is a recently introduced atypical antipsychotic. Although adverse effects are mainly mild, more serious infrequent adverse effects including leucopenia are mentioned. METHOD: We describe three case-reports concerning haematological adverse effects of quetiapine. RESULTS: Quetiapine was associated with leucopenia in two patients and clinically apparent agranulocytosis in one patient. CONCLUSION: Although a definite association has not been proven, clinicians should be aware of the possibility of agranulocytosis while using quetiapine. Further post-marketing surveys are required.
OBJECTIVE:Quetiapine is a recently introduced atypical antipsychotic. Although adverse effects are mainly mild, more serious infrequent adverse effects including leucopenia are mentioned. METHOD: We describe three case-reports concerning haematological adverse effects of quetiapine. RESULTS:Quetiapine was associated with leucopenia in two patients and clinically apparent agranulocytosis in one patient. CONCLUSION: Although a definite association has not been proven, clinicians should be aware of the possibility of agranulocytosis while using quetiapine. Further post-marketing surveys are required.
Authors: Samuel S Allemann; Delia Bornand; Balthasar Hug; Kurt E Hersberger; Isabelle Arnet Journal: Biomed Res Int Date: 2015-10-11 Impact factor: 3.411