Literature DB >> 11720919

Online prescribing of sildanefil (Viagra) on the world wide web.

G Eysenbach1.   

Abstract

BACKGROUND: A growing number of prescription medicines such as Viagra are offered and sold directly to consumers on the Internet. Little is known about the structure and "quality" of these "virtual pharmacies" in terms of how responsibly "online-prescriptions" are actually issued.
OBJECTIVE: To determine to what extent Viagra is sold on the Internet despite clear contraindications.
METHODS: The World Wide Web was searched for companies who offer to issue prescriptions for Viagra online or sell Viagra without prescription. We pretended to be a patient in which the ordered drug (Viagra) is clearly contraindicated, and tried to obtain an online prescription for this drug on the Internet. Our test case was as a 69-year-old woman giving a sexual history of having "no orgasm," with obesity (165 cm/78 kg), coronary artery disease, and hypertension, and taking captopril, pravachol, atenolol, and erythromycin.
RESULTS: Twenty-two distinct companies were identified, consisting of three different types: 2 required a written prescription by a "real" physician, 9 dispensed the drug without any prescription at all, and 11 issued an "online prescription" after an alleged physician reviewed the online order form containing medical questions. We tested 10 of the latter type, among them 8 based in the USA. We ordered a total of 66 pills worth US$ 1,802.84. Three companies, among them both European companies, delivered within 6, 10, and 34 days respectively, despite Viagra being clearly contraindicated. In 80% no complete history was taken, in 70% inappropriate medical terminology was used, and in only 2 cases was the order form reviewed by a physician who identified himself.
CONCLUSIONS: Although a surprisingly high number of Internet pharmacies declined delivery, the public should be alerted to the risks involved with prescription drug prescribing and dispensing via the Internet.

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Year:  1999        PMID: 11720919      PMCID: PMC1761711          DOI: 10.2196/jmir.1.2.e10

Source DB:  PubMed          Journal:  J Med Internet Res        ISSN: 1438-8871            Impact factor:   5.428


  2 in total

1.  Evaluation of cyberdocs.

Authors:  G Eysenbach; T L Diepgen
Journal:  Lancet       Date:  1998-11-07       Impact factor: 79.321

Review 2.  ACC/AHA expert consensus document. Use of sildenafil (Viagra) in patients with cardiovascular disease. American College of Cardiology/American Heart Association.

Authors:  M D Cheitlin; A M Hutter; R G Brindis; P Ganz; S Kaul; R O Russell; R M Zusman
Journal:  J Am Coll Cardiol       Date:  1999-01       Impact factor: 24.094

  2 in total
  12 in total

1.  Code of conduct is needed for publishing raw data.

Authors:  G Eysenbach; E R Sa
Journal:  BMJ       Date:  2001-07-21

2.  Quality of drug information on the World Wide Web and strategies to improve pages with poor information quality. An intervention study on pages about sildenafil.

Authors:  Meret Martin-Facklam; Michael Kostrzewa; Peter Martin; Walter E Haefeli
Journal:  Br J Clin Pharmacol       Date:  2004-01       Impact factor: 4.335

3.  A detailed analysis of online pharmacy characteristics to inform safe usage by patients.

Authors:  Bassam M Alwon; Gennifer Solomon; Faseeha Hussain; David J Wright
Journal:  Int J Clin Pharm       Date:  2015-01-07

4.  Sexual medicine: Online risks to health--the problem of counterfeit drugs.

Authors:  Bryan A Liang; Tim K Mackey
Journal:  Nat Rev Urol       Date:  2012-07-24       Impact factor: 14.432

Review 5.  Quality of online pharmacies and websites selling prescription drugs: a systematic review.

Authors:  Grazia Orizio; Anna Merla; Peter J Schulz; Umberto Gelatti
Journal:  J Med Internet Res       Date:  2011-09-30       Impact factor: 5.428

6.  Packaging and labeling of pharmaceutical products obtained from the internet.

Authors:  Michael Veronin
Journal:  J Med Internet Res       Date:  2011-02-15       Impact factor: 5.428

7.  Online prescriptions of pharmaceuticals: where is the evidence for harm or for benefit? A call for papers--and for reflection.

Authors:  G Eysenbach
Journal:  J Med Internet Res       Date:  2001 Jan-Mar       Impact factor: 5.428

Review 8.  Counterfeit phosphodiesterase type 5 inhibitors pose significant safety risks.

Authors:  G Jackson; S Arver; I Banks; V J Stecher
Journal:  Int J Clin Pract       Date:  2010-01-18       Impact factor: 2.503

9.  Swiss community pharmacies' on the Web and pharmacists' experiences with E-commerce: longitudinal study and Internet-based questionnaire survey.

Authors:  Simon Zehnder; Rudolf Bruppacher; Hans Ruppanner; Kurt E Hersberger
Journal:  J Med Internet Res       Date:  2004-03-03       Impact factor: 5.428

10.  Health outcomes in patients using no-prescription online pharmacies to purchase prescription drugs.

Authors:  Theodore J Cicero; Matthew Stephen Ellis
Journal:  J Med Internet Res       Date:  2012-12-06       Impact factor: 5.428

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