| Literature DB >> 11720851 |
D Kim1, L Wang, C G Caldwell, P Chen, P E Finke, B Oates, M MacCoss, S G Mills, L Malkowitz, S L Gould, J A DeMartino, M S Springer, D Hazuda, M Miller, J Kessler, R Danzeisen, G Carver, A Carella, K Holmes, J Lineberger, W A Schleif, E A Emini.
Abstract
A series of hydantoin derivatives has been discovered as highly potent nonpeptide antagonists for the human CCR5 receptor. The synthesis, SAR, and biological profiles of this class of antagonists are described.Entities:
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Year: 2001 PMID: 11720851 DOI: 10.1016/s0960-894x(01)00654-0
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN: 0960-894X Impact factor: 2.823