| Literature DB >> 11720537 |
J Tanaka1, G Marriott, T Higa, T Higa.
Abstract
Two new labdane-class diterpenes, cacofurans A (1) and B (2), have been isolated from a sponge Cacospongia sp. Their structures were determined by analyzing spectroscopic data, by chemical transformations, and by X-ray diffraction. Cacofurans 1 and 2 inhibited the development of fertilized sea urchin eggs at concentrations of 0.5 and 5 microg/mL and showed an actin-disrupting effect on the NBT-II cell line at 10 microg/mL.Entities:
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Year: 2001 PMID： 11720537 DOI： 10.1021/np010203g
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050