Literature DB >> 11719622

Depression, mood state, and back pain during microgravity simulated by bed rest.

J R Styf1, K Hutchinson, S G Carlsson, A R Hargens.   

Abstract

OBJECTIVE: The objective of this study was to develop a ground-based model for spinal adaptation to microgravity and to study the effects of spinal adaptation on depression, mood state, and pain intensity.
METHODS: We investigated back pain, mood state, and depression in six subjects, all of whom were exposed to microgravity, simulated by two forms of bed rest, for 3 days. One form consisted of bed rest with 6 degrees of head-down tilt and balanced traction, and the other consisted of horizontal bed rest. Subjects had a 2-week period of recovery between the studies. The effects of bed rest on pain intensity in the lower back, depression, and mood state were investigated.
RESULTS: Subjects experienced significantly more intense lower back pain, lower hemisphere abdominal pain, headache, and leg pain during head-down tilt bed rest. They had higher scores on the Beck Depression Inventory (ie, were more depressed) and significantly lower scores on the activity scale of the Bond-Lader questionnaire.
CONCLUSIONS: Bed rest with 6 degrees of head-down tilt may be a better experimental model than horizontal bed rest for inducing the pain and psychosomatic reactions experienced in microgravity. Head-down tilt with balanced traction may be a useful method to induce low back pain, mood changes, and altered self-rated activity level in bed rest studies.

Entities:  

Keywords:  NASA Center ARC; NASA Discipline Musculoskeletal

Mesh:

Year:  2001        PMID: 11719622     DOI: 10.1097/00006842-200111000-00002

Source DB:  PubMed          Journal:  Psychosom Med        ISSN: 0033-3174            Impact factor:   4.312


  11 in total

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6.  Decreasing ventromedial prefrontal cortex deactivation in risky decision making after simulated microgravity: effects of -6° head-down tilt bed rest.

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10.  Long-term effects of simulated microgravity and/or chronic exposure to low-dose gamma radiation on behavior and blood-brain barrier integrity.

Authors:  John A Bellone; Peter S Gifford; Nina C Nishiyama; Richard E Hartman; Xiao Wen Mao
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