Literature DB >> 11718938

Chitosans for gene delivery.

G Borchard1.   

Abstract

Efficient non-viral gene delivery based on cationic polymers as DNA-condensing agents is dependent on a variety of factors, e.g. complex size, complex stability, toxicity, immunogenicity, protection against DNase degradation, and intracellular trafficking and processing of the DNA. This review examines the advances in the application of chitosan and chitosan derivatives to non-viral gene delivery, and gives an overview of transfection studies which have been performed recently using chitosans as transfection agents.

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Year:  2001        PMID： 11718938     DOI： 10.1016/s0169-409x(01)00198-3

Source DB:  PubMed          Journal:  Adv Drug Deliv Rev        ISSN： 0169-409X            Impact factor:   15.470


  60 in total

1.  Transfection of mEpo gene to intestinal epithelium in vivo mediated by oral delivery of chitosan-DNA nanoparticles.

Authors:  Jing Chen; Wu-Li Yang; Ge Li; Ji Qian; Jing-Lun Xue; Shou-Kuan Fu; Da-Ru Lu
Journal:  World J Gastroenterol       Date:  2004-01       Impact factor: 5.742

2.  Fabrication of novel biofibers by coating silk fibroin with chitosan impregnated with silver nanoparticles.

Authors:  K Karthikeyan; S Sekar; M Pandima Devi; S Inbasekaran; C H Lakshminarasaiah; T P Sastry
Journal:  J Mater Sci Mater Med       Date:  2011-11-01       Impact factor: 3.896

Review 3.  Recent advancement of chitosan-based nanoparticles for oral controlled delivery of insulin and other therapeutic agents.

Authors:  Anumita Chaudhury; Surajit Das
Journal:  AAPS PharmSciTech       Date:  2010-12-11       Impact factor: 3.246

4.  Understanding intracellular transport processes pertinent to synthetic gene delivery via stochastic simulations and sensitivity analyses.

Authors:  Anh-Tuan Dinh; Chinmay Pangarkar; Theo Theofanous; Samir Mitragotri
Journal:  Biophys J       Date:  2006-11-03       Impact factor: 4.033

5.  Direct force measurements between siRNA and chitosan molecules using force spectroscopy.

Authors:  Sailong Xu; Mingdong Dong; Xiudong Liu; Kenneth A Howard; Jørgen Kjems; Flemming Besenbacher
Journal:  Biophys J       Date:  2007-05-04       Impact factor: 4.033

6.  Biocompatibility evaluation of N,O-hexanoyl chitosan as a biodegradable hydrophobic polycation for controlled drug release.

Authors:  Chaonan Xu; Hui Pan; Hongliang Jiang; Guping Tang; Weiliam Chen
Journal:  J Mater Sci Mater Med       Date:  2008-02-12       Impact factor: 3.896

7.  Chitosan/pshRNA plasmid nanoparticles targeting MDR1 gene reverse paclitaxel resistance in ovarian cancer cells.

Authors:  Yan Yang; Zehua Wang; Minfang Li; Shi Lu
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2009-04-28

8.  Poly(2 deoxy 2 methacrylamido glucopyranose) b Poly(methacrylate amine)s: Optimization of Diblock Glycopol ycations for Nucleic Acid Delivery.

Authors:  Haibo Li; Mallory A Cortez; Haley R Phillips; Yaoying Wu; Theresa M Reineke
Journal:  ACS Macro Lett       Date:  2013-03-19       Impact factor: 6.903

9.  RNA interference with special reference to combating viruses of crustacea.

Authors:  Kathy La Fauce; Leigh Owens
Journal:  Indian J Virol       Date:  2012-08-14

Review 10.  Polymeric nanoparticles: potent vectors for vaccine delivery targeting cancer and infectious diseases.

Authors:  Azam Bolhassani; Shabnam Javanzad; Tayebeh Saleh; Mehrdad Hashemi; Mohammad Reza Aghasadeghi; Seyed Mehdi Sadat
Journal:  Hum Vaccin Immunother       Date:  2013-10-15       Impact factor: 3.452
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