Literature DB >> 11717952

Quantitative assessment of Parkinson's disease deficits.

T Zhang1, G Wei, Z Yan, M Ding, C Li, H Ding, S Xu.   

Abstract

OBJECTIVE: To quantitatively analyze the tremor and rigidity due to Parkinson's disease.
METHODS: 38 patients with Parkinson's disease (PD) ranging in age from 45 to 72 years and 211 normal subjects aged from 16 to 76 years were investigated. The frequency and range of tremor, the muscle tone of the upper limbs in elbow were detected by a computerized video motion detecting system and a new invented apparatus which can detects skeletal muscle tone.
RESULTS: For the PD patients, the frequency of resting tremors was detected in 4 to 6 per second. For extensor and flexor in the PD patients, the value of muscle tone was higher than that of normal subjects and the value of muscle tone in flexor was higher than that of extensor. The rigidity increased gradually with repeat passive movement. The curves of rigidity were shown on computer screen or printed out. The data of rigidity were compared with the M-A Scale. A patient who was suspected to suffer from PD above by the equipments and found the muscle tone was higher than normal. In another PD patient the rigidity was obvious at one side and the muscle tone in "normal side" was also high. These equipments were used to record changes of rigidity and tremor in one more PD patient taking with different drugs in order to see the drug effect.
CONCLUSION: Quantitative methods are useful to analyse the motion disorders due to PD.

Entities:  

Mesh:

Year:  1999        PMID: 11717952

Source DB:  PubMed          Journal:  Chin Med J (Engl)        ISSN: 0366-6999            Impact factor:   2.628


  6 in total

1.  Can stooped posture explain multidirectional postural instability in patients with Parkinson's disease?

Authors:  Jesse V Jacobs; Diana M Dimitrova; John G Nutt; Fay B Horak
Journal:  Exp Brain Res       Date:  2005-08-12       Impact factor: 1.972

2.  Reduced performance in balance, walking and turning tasks is associated with increased neck tone in Parkinson's disease.

Authors:  Erika Franzén; Caroline Paquette; Victor S Gurfinkel; Paul J Cordo; John G Nutt; Fay B Horak
Journal:  Exp Neurol       Date:  2009-06-30       Impact factor: 5.330

3.  Axial hypertonicity in Parkinson's disease: direct measurements of trunk and hip torque.

Authors:  W G Wright; V S Gurfinkel; J Nutt; F B Horak; P J Cordo
Journal:  Exp Neurol       Date:  2007-07-17       Impact factor: 5.330

Review 4.  Neurological tremor: sensors, signal processing and emerging applications.

Authors:  Giuliana Grimaldi; Mario Manto
Journal:  Sensors (Basel)       Date:  2010-02-24       Impact factor: 3.576

Review 5.  Therapeutic effects of melatonin receptor agonists on sleep and comorbid disorders.

Authors:  Moshe Laudon; Anat Frydman-Marom
Journal:  Int J Mol Sci       Date:  2014-09-09       Impact factor: 5.923

6.  Measurement and Correction of Stooped Posture during Gait Using Wearable Sensors in Patients with Parkinsonism: A Preliminary Study.

Authors:  Se Hoon Kim; Seo Jung Yun; Quoc Khanh Dang; Youngjoon Chee; Sun Gun Chung; Byung-Mo Oh; Keewon Kim; Han Gil Seo
Journal:  Sensors (Basel)       Date:  2021-03-30       Impact factor: 3.576

  6 in total

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