Literature DB >> 1171695

Determination of benzene and toluene in blood by means of a syringe-equilibration method using a small amount of blood.

A Sato, T Nakajima, Y Fujiwara.   

Abstract

A gas chromatographic determination of benzene and toluene in blood with a small amount of blood sample, 0.02 or 0.1 ml, is described. In the method an aliquot of the blood sample in a sealed hypodermic syringe of 2 ml capacity is equilibrated at 37 degrees C in a thermo-regulated water-bath. After establishing equilibrium 1 ml of overlying air is submitted to gas chromatographic analysis. The value of this method was verified by experiments in which men, rabbits, and rats were exposed to benzene and toluene mixtures of various concentrations.

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Year:  1975        PMID: 1171695      PMCID: PMC1008060          DOI: 10.1136/oem.32.3.210

Source DB:  PubMed          Journal:  Br J Ind Med        ISSN: 0007-1072


  10 in total

1.  FLAME IONIZATION DETECTION OF VOLATILE ORGANIC ANESTHETICS IN BLOOD, GASES AND TISSUES.

Authors:  H J LOWE
Journal:  Anesthesiology       Date:  1964 Nov-Dec       Impact factor: 7.892

2.  A technique for the analysis of methoxyflurane in blood by gas chromatography.

Authors:  P L Jones; M J Molloy; M Rosen
Journal:  Br J Anaesth       Date:  1972-02       Impact factor: 9.166

3.  A rapid direct-injection method for measuring volatile anesthetics in whole blood.

Authors:  M J Cousins; R I Mazze
Journal:  Anesthesiology       Date:  1972-03       Impact factor: 7.892

4.  A simplified mhod for the measurement of volatile anesthetics in blood by gas chromatography.

Authors:  B R Fink; K Mikawa
Journal:  Anesthesiology       Date:  1970-05       Impact factor: 7.892

5.  [Gas chromatographic analysis of volatile anesthetics in the blood by an ampule-crash method].

Authors:  Y Okuda
Journal:  Masui       Date:  1968-05

6.  [Gaschromatographic determination of benzene and toluene in small amounts of blood].

Authors:  D Szadkowski; U Schröter; H G Essing; K H Schaller; G Lehnert
Journal:  Int Arch Arbeitsmed       Date:  1971

Review 7.  Pharmacokinetics of drug action.

Authors:  G Levy; M Gibaldi
Journal:  Annu Rev Pharmacol       Date:  1972       Impact factor: 13.820

8.  The determination of hydrocarbon anesthetics in blood by gas chromatography.

Authors:  R A Utler; A B Kelly; J Zapp
Journal:  Anesthesiology       Date:  1967 Jul-Aug       Impact factor: 7.892

9.  Gas chromatographic analysis of inhalation anesthetics in whole blood by an equilibration method.

Authors:  H Yamamura; B Wakasugi; S Sato; Y Takebe
Journal:  Anesthesiology       Date:  1966 May-Jun       Impact factor: 7.892

10.  Direct injection method for gas chromatographic measurement of inhalation anesthetics in whole blood and tissues.

Authors:  T Yokota; Y Hitomi; K Ohta; F Kosaka
Journal:  Anesthesiology       Date:  1967 Nov-Dec       Impact factor: 7.892

  10 in total
  17 in total

1.  Kinetic studies on sex difference in susceptibility to chronic benzene intoxication--with special reference to body fat content.

Authors:  A Sato; T Nakajima; Y Fujiwara; N Murayama
Journal:  Br J Ind Med       Date:  1975-11

2.  Circadian variations of acute toxicity and blood and brain concentrations of inhaled toluene in rats.

Authors:  I Harabuchi; R Kishi; T Ikeda; H Kiyosawa; H Miyake
Journal:  Br J Ind Med       Date:  1993-03

3.  A pharmacokinetic model to study the excretion of trichloroethylene and its metabolites after an inhalation exposure.

Authors:  A Sato; T Nakajima; Y Fujiwara; N Murayama
Journal:  Br J Ind Med       Date:  1977-02

4.  Enzyme induction by ethanol consumption affects the pharmacokinetics of inhaled m-xylene only at high levels of exposure.

Authors:  T Kaneko; P Y Wang; A Sato
Journal:  Arch Toxicol       Date:  1993       Impact factor: 5.153

5.  Differences following skin or inhalation exposure in the absorption and excretion kinetics of trichloroethylene and toluene.

Authors:  A Sato; T Nakajima
Journal:  Br J Ind Med       Date:  1978-02

6.  Monitoring of workers exposed to a mixture of toluene, styrene and methanol vapours by means of diffusive air sampling, blood analysis and urinalysis.

Authors:  T Kawai; T Yasugi; K Mizunuma; S Horiguchi; I Morioka; K Miyashita; Y Uchida; M Ikeda
Journal:  Int Arch Occup Environ Health       Date:  1992       Impact factor: 3.015

7.  Effects of chronic ethanol consumption on hepatic metabolism of aromatic and chlorinated hydrocarbons in rats.

Authors:  A Sato; T Nakajima; Y Koyama
Journal:  Br J Ind Med       Date:  1980-11

8.  Dose and route dependency of metabolism and toxicity of chloroform in ethanol-treated rats.

Authors:  P Y Wang; T Kaneko; H Tsukada; A Sato
Journal:  Arch Toxicol       Date:  1994       Impact factor: 5.153

9.  Effects of ethanol and phenobarbital treatments on the pharmacokinetics of toluene in rats.

Authors:  R S Wang; T Nakajima
Journal:  Br J Ind Med       Date:  1992-02

10.  Effect of various exposure scenarios on the biological monitoring of organic solvents in alveolar air. I. Toluene and m-xylene.

Authors:  S Laparé; R Tardif; J Brodeur
Journal:  Int Arch Occup Environ Health       Date:  1993       Impact factor: 3.015

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