Literature DB >> 11715438

[CT and MR imaging of germinomas arising in basal ganglia and thalamus].

Y Lin1, P Gao.   

Abstract

OBJECTIVE: To evaluate the role of CT and MR imaging in diagnosing germinomas arising in the basal ganglia and thalamus.
METHODS: MR imaging of 11 boys (ranging in age from 3-15 years with a median of 10.7 years) with germinomas arising from the basal ganglia and thalamus was reviewed retrospectively and the imaging findings were compared with the features of 86 germinomas in other regions. The tumors located at basal ganglia in 9 and at thalamus in 2. All diagnosis was proved operatively and pathologyically. Five cases were studied using both CT and MR, 4 were examined with MR and 2 with CT only.
RESULTS: In this series of 11 tumors, 9 were located in the basal ganglia and 2 in the thalamus. The shape of six tumors was global and 5 was lobulated. The cystic components or necrosis were intratumoral in 5 patients and hemorrhage in 4. Patchy enhancement was found in 9 patients and ring-enhancing lesions in 2. Tumor spread oppositely in 4 patients. Five patients demonstrated cortical atrophy ipsilaterally.
CONCLUSION: The germinomas arising from the basal ganglia and thalamus have sex, location and imaging characteristics. Therefore, it is possible to make preoperative diagnosis using CT or MR.

Entities:  

Mesh:

Year:  1999        PMID: 11715438

Source DB:  PubMed          Journal:  Zhonghua Yi Xue Za Zhi        ISSN: 0376-2491


  5 in total

1.  Is biopsy needed to guide management for all patients with presumed intracranial ectopic germinomas.

Authors:  Chenglin Tian; Chuanqiang Pu; WeiPing Wu; Xusheng Huang; Senyang Lang; Shengyuan Yu; Jiatang Zhang; Dehui Huang; Shuxiang Cui
Journal:  J Neurooncol       Date:  2008-10-26       Impact factor: 4.130

2.  Clinical features, radiologic findings, and treatment of pediatric germ cell tumors involving the basal ganglia and thalamus: a retrospective series of 15 cases at a single center.

Authors:  Mengmeng Wang; Peizhi Zhou; Shizhen Zhang; Xueyou Liu; Liang Lv; Zeming Wang; Feng Ye; Yan Ju; Shu Jiang
Journal:  Childs Nerv Syst       Date:  2017-10-24       Impact factor: 1.475

3.  Germinoma involving the basal ganglia in children.

Authors:  Tai-Tong Wong; Y W Chen; Wan-Yuo Guo; Kai-Ping Chang; Donald M Ho; Sang-Hue Yen
Journal:  Childs Nerv Syst       Date:  2007-09-29       Impact factor: 1.475

4.  Germinoma with synchronous involvement of midline and off-midline structures associated with progressive hemiparesis and hemiatrophy in a young adult.

Authors:  S Sartori; A M Laverda; M Calderone; C Carollo; E Viscardi; R Faggin; G Perilongo
Journal:  Childs Nerv Syst       Date:  2007-07-03       Impact factor: 1.475

Review 5.  Radiologic features of primary intracranial ectopic germinomas: Case reports and literature review.

Authors:  Xin-Hua Wei; Hui-Cong Shen; Shou-Xian Tang; Cui-Hua Gao; Ji-Liang Ren; Lin Ai; Jian-Ping Dai
Journal:  Medicine (Baltimore)       Date:  2016-12       Impact factor: 1.889

  5 in total

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