Literature DB >> 11714227

Ammocidin, a new apoptosis inducer in ras-dependent cells from Saccharothrix sp. II. Physico-chemical properties and structure elucidation.

R Murakami1, T Tomikawa, K Shin-ya, J Shinozaki, T Kajiura, H Seto, Y Hayakawa.   

Abstract

The structure of ammocidin, a new apoptosis inducer in Ras-dependent cells from Saccharothrix sp. AJ9571, was elucidated to be as shown in Fig. 1 by NMR and degradation studies. Ammocidin consists of a 20-membered macrolide ring and three deoxy sugars identified as 6-deoxy-L-glucose, D-digitoxose and D-olivomycose.

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Year:  2001        PMID： 11714227     DOI： 10.7164/antibiotics.54.714

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  5 in total

Review 1.  A comprehensive review of glycosylated bacterial natural products.

Authors:  Sherif I Elshahawi; Khaled A Shaaban; Madan K Kharel; Jon S Thorson
Journal:  Chem Soc Rev       Date:  2015-11-07       Impact factor: 54.564

2.  Combinatorial biosynthesis of antitumor deoxysugar pathways in Streptomyces griseus: Reconstitution of "unnatural natural gene clusters" for the biosynthesis of four 2,6-D-dideoxyhexoses.

Authors:  María Pérez; Felipe Lombó; Irfan Baig; Alfredo F Braña; Jürgen Rohr; José A Salas; Carmen Méndez
Journal:  Appl Environ Microbiol       Date:  2006-10       Impact factor: 4.792

3.  Amycolatopsins A-C: antimycobacterial glycosylated polyketide macrolides from the Australian soil Amycolatopsis sp. MST-108494.

Authors:  Zeinab G Khalil; Angela A Salim; Daniel Vuong; Andrew Crombie; Ernest Lacey; Antje Blumenthal; Robert J Capon
Journal:  J Antibiot (Tokyo)       Date:  2017-10-25       Impact factor: 2.649

4.  18O assisted analysis of a γ,δ-epoxyketone cyclization: synthesis of the C16-C28 fragment of ammocidin D.

Authors:  Stephen T Chau; Yoichi Hayakawa; Gary A Sulikowski
Journal:  Org Lett       Date:  2011-01-19       Impact factor: 6.005

5.  Bioprospecting of Soil-Derived Actinobacteria Along the Alar-Hotan Desert Highway in the Taklamakan Desert.

Authors:  Shaowei Liu; Ting Wang; Qinpei Lu; Feina Li; Gang Wu; Zhongke Jiang; Xugela Habden; Lin Liu; Xiaolin Zhang; Dmitry A Lukianov; Ilya A Osterman; Petr V Sergiev; Olga A Dontsova; Chenghang Sun
Journal:  Front Microbiol       Date:  2021-03-15       Impact factor: 5.640
  5 in total

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