| Literature DB >> 11713795 |
Abstract
A new approach to the chemical control of respiratory syncytial virus infection is reviewed in the context of the biology of the virus and previous treatment approaches. Conjugation of the interferon action mediator, 2',5'-oligoadenylate (2-5A), to antisense agents provides a strategy for the selective ablation of RNA. This application of this technology to respiratory syncytial virus has provided a potent selective inhibitor of virus replication.Entities:
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Year: 1999 PMID： 11713795
Source DB: PubMed Journal: Curr Opin Mol Ther ISSN： 1464-8431