Literature DB >> 11711284

Syntheses and biological evaluation of alkanediamines as antioxidant and hypolipidemic agents.

S Batra1, A P Bhaduri, B S Joshi, R Roy, A K Khanna, R Chander.   

Abstract

A new series of compounds belonging to N,N'- [bis (1-aryl-6-hydroxy-hex-2-ene-1-one-3-yl)-1,n-alkanediamines (2-5a-f) have been synthesized and evaluated for antioxidant and hypolipidemic activities. Amongst all the synthesized compounds, seven compounds namely 2c, 2e, 4c, 5b, 5c, 5e and 5f exhibit potent antioxidant activity. These compounds have also been evaluated for hypolipidemic activity.

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Year:  2001        PMID: 11711284     DOI: 10.1016/s0968-0896(01)00185-7

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN: 0968-0896            Impact factor:   3.641


  2 in total

1.  Leishmania donovani Dipeptidylcarboxypeptidase Inhibitor as a Potential Oral Treatment for Visceral Leishmaniasis.

Authors:  Karthik Ramalingam; Sonali Gangwar; Deep Chandra Balodi; Apeksha Anand; Shailendra Yadav; Subhasish Biswas; Anil Kumar Karunakaran Sasikala; Kailash Chand Gupta; Sanjay Batra; Neena Goyal
Journal:  Antimicrob Agents Chemother       Date:  2022-07-19       Impact factor: 5.938

2.  Development of luciferase expressing Leishmania donovani axenic amastigotes as primary model for in vitro screening of antileishmanial compounds.

Authors:  Sonali Gangwar; Neena Goyal
Journal:  Curr Microbiol       Date:  2012-09-04       Impact factor: 2.188

  2 in total

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