| Literature DB >> 1171016 |
B V Clineschmidt, A B Pflueger, P R Bunting, J C McGuffin, R J Ballentine.
Abstract
BE-2254, 2-[beta-(4-hydroxyphenyl)-ethylaminomethyl]-tetralone, (ED50 = 3.4 mg/kg i.p.) was about equal to chlorpromazine (ED50 = 4.4) as an antagonist of central noradrenergic receptor stimulation produced by clonidine (enhancement of the flexor reflex in spinalized rats). Haloperidol and phentolamine had essentially no effect at 9 mg/kg i.p...Entities:
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Year: 1975 PMID: 1171016 DOI: 10.1016/0014-2999(75)90294-0
Source DB: PubMed Journal: Eur J Pharmacol ISSN: 0014-2999 Impact factor: 4.432