Literature DB >> 11710090

Definition of and mechanism for opioid-induced sedation.

S Young-McCaughan1, C Miaskowski.   

Abstract

Although sedation is acknowledged to be one of the most common side effects of opioid analgesics, the mechanisms and characteristics of this phenomenon remain elusive, and research in this area is extremely limited. This report integrates research findings on the mechanism of action of opioids with research findings on the phenomenon of consciousness to develop a model of how opioids may act in the central nervous system to produce sedation. Based on this integration, a definition of opioid-induced sedation is proposed to encourage dialogue and research on this perplexing and clinically significant phenomenon.

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Year:  2001        PMID： 11710090     DOI： 10.1053/jpmn.2001.25012

Source DB:  PubMed          Journal:  Pain Manag Nurs        ISSN： 1524-9042            Impact factor:   1.929


  11 in total

1.  Gender Differences in Sleep Problems Among Drug Users.

Authors:  Haoyu He; Jinsong Tang; Tieqiao Liu; Wei Hao; Yanhui Liao
Journal:  Front Psychiatry       Date:  2020-08-12       Impact factor: 4.157

2.  Subjective daytime sleepiness and daytime function in patients on stable methadone maintenance treatment: possible mechanisms.

Authors:  David Wang; Harry Teichtahl; Cathy Goodman; Olaf Drummer; Ronald R Grunstein; Ian Kronborg
Journal:  J Clin Sleep Med       Date:  2008-12-15       Impact factor: 4.062

Review 3.  Sleep dysregulation in binge eating disorder and "food addiction": the orexin (hypocretin) system as a potential neurobiological link.

Authors:  Jacqueline B Mehr; Deborah Mitchison; Hannah E Bowrey; Morgan H James
Journal:  Neuropsychopharmacology       Date:  2021-06-18       Impact factor: 7.853

4.  Aspiration pneumonitis caused by delayed respiratory depression following intrathecal morphine administration.

Authors:  Bo Young Whang; Seong Whan Jeong; Jeong Gill Leem; Young Ki Kim
Journal:  Korean J Pain       Date:  2012-04-04

5.  Cebranopadol reduces cocaine self-administration in male rats: Dose, treatment and safety consideration.

Authors:  Huimei Wei; Ting Zhang; Chang-Guo Zhan; Fang Zheng
Journal:  Neuropharmacology       Date:  2020-05-08       Impact factor: 5.273

6.  Effects of an intrathecal TRPV1 antagonist, SB366791, on morphine-induced itch, body temperature, and antinociception in mice.

Authors:  Satoshi Sakakibara; Noritaka Imamachi; Manabu Sakakihara; Yukiko Katsube; Mai Hattori; Yoji Saito
Journal:  J Pain Res       Date:  2019-08-28       Impact factor: 3.133

7.  Ultrasound-guided Modified Parasternal Intercostal Nerve Block: Role of Preemptive Analgesic Adjunct for Mitigating Poststernotomy Pain.

Authors:  Santhosh Vilvanathan; M S Saravanababu; Rupa Sreedhar; Shinivas Vitthal Gadhinglajkar; Prasanta Kumar Dash; Subin Sukesan
Journal:  Anesth Essays Res       Date:  2020-10-12

Review 8.  Sleep abnormalities associated with alcohol, cannabis, cocaine, and opiate use: a comprehensive review.

Authors:  Gustavo A Angarita; Nazli Emadi; Sarah Hodges; Peter T Morgan
Journal:  Addict Sci Clin Pract       Date:  2016-04-26

9.  Dexmedetomidine - Commonly Used in Functional Imaging Studies - Increases Susceptibility to Seizures in Rats But Not in Wild Type Mice.

Authors:  Aleksandra Bortel; Roland Pilgram; Ze Shan Yao; Amir Shmuel
Journal:  Front Neurosci       Date:  2020-10-29       Impact factor: 4.677

10.  Opioids and alpha-2-agonists for analgesia and sedation in newborn infants: protocol of a systematic review.

Authors:  Mari Kinoshita; Katarzyna Stempel; Israel Junior Borges do Nascimento; Dhashini Naidu Vejayaram; Elisabeth Norman; Matteo Bruschettini
Journal:  Syst Rev       Date:  2020-08-20
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