| Literature DB >> 11709363 |
S W Kamau1, F Grimm, A B Hehl.
Abstract
Transgenic Leishmania infantum promastigotes, which constitutively express green fluorescent protein (GFP) in their cytoplasm, were used to monitor the effects of antileishmanial compounds in real time. The GFP-based assay provided a reliable measure of drug-induced inhibitory effects on protein expression, resulting in a dynamic picture of the responses of leishmanial promastigotes to the compounds tested.Entities:
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Year: 2001 PMID: 11709363 PMCID: PMC90892 DOI: 10.1128/AAC.45.12.3654-3656.2001
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191