Literature DB >> 11707285

In silico screening for tumour-specific expressed sequences in human genome.

A V Baranova1, A V Lobashev, D V Ivanov, L L Krukovskaya, N K Yankovsky, A P Kozlov.   

Abstract

A computer-based differential display tool named HsAnalyst has been developed and successfully used for the comparison of expression patterns in a set of tumours versus a set of normal tissues. A list of EST clusters highly represented in tumours and rarely observed in normal tissues has been developed as a resulting output file of the program. These differentially expressed EST clusters (genes) can be useful for developing new tumour markers and prognostic indicators for a wide set of human malignancies. Tumour-specific protein-coding genes may be considered a manifestation of tumour-specific gene expression.

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Year:  2001        PMID： 11707285     DOI： 10.1016/s0014-5793(01)03028-9

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  16 in total

1.  Sequence conservation, relative isoform frequencies, and nonsense-mediated decay in evolutionarily conserved alternative splicing.

Authors:  Daehyun Baek; Phil Green
Journal:  Proc Natl Acad Sci U S A       Date:  2005-08-25       Impact factor: 11.205

2.  Binding properties and dynamic localization of an alternative isoform of the cap-binding complex subunit CBP20.

Authors:  Marta Pabis; Noa Neufeld; Yaron Shav-Tal; Karla M Neugebauer
Journal:  Nucleus       Date:  2010 Sep-Oct       Impact factor: 4.197

3.  Quantitative gene expression profiles in real time from expressed sequence tag databases.

Authors:  Vincent A Funari; Konstantin Voevodski; Dimitry Leyfer; Laura Yerkes; Donald Cramer; Dean R Tolan
Journal:  Gene Expr       Date:  2010

4.  A genome-wide survey demonstrates widespread non-linear mRNA in expressed sequences from multiple species.

Authors:  Richard J Dixon; Ian C Eperon; Laurence Hall; Nilesh J Samani
Journal:  Nucleic Acids Res       Date:  2005-10-19       Impact factor: 16.971

5.  The importance of being divisible by three in alternative splicing.

Authors:  Alon Magen; Gil Ast
Journal:  Nucleic Acids Res       Date:  2005-09-28       Impact factor: 16.971

6.  GBA server: EST-based digital gene expression profiling.

Authors:  Xin Wu; Michael G Walker; Jingchu Luo; Liping Wei
Journal:  Nucleic Acids Res       Date:  2005-07-01       Impact factor: 16.971

7.  In silico whole-genome screening for cancer-related single-nucleotide polymorphisms located in human mRNA untranslated regions.

Authors:  Abdel Aouacheria; Vincent Navratil; Ricardo López-Pérez; Norma C Gutiérrez; Alexander Churkin; Danny Barash; Dominique Mouchiroud; Christian Gautier
Journal:  BMC Genomics       Date:  2007-01-03       Impact factor: 3.969

8.  Computational and experimental analysis identifies Arabidopsis genes specifically expressed during early seed development.

Authors:  Cristian Becerra; Pere Puigdomenech; Carlos M Vicient
Journal:  BMC Genomics       Date:  2006-02-28       Impact factor: 3.969

9.  Bioinformatic screening of human ESTs for differentially expressed genes in normal and tumor tissues.

Authors:  Abdel Aouacheria; Vincent Navratil; Audrey Barthelaix; Dominique Mouchiroud; Christian Gautier
Journal:  BMC Genomics       Date:  2006-04-26       Impact factor: 3.969

10.  Evolutionarily new sequences expressed in tumors.

Authors:  Andrei P Kozlov; Yuri P Galachyants; Ilya V Dukhovlinov; Nickolai A Samusik; Ancha V Baranova; Dmitry E Polev; Larisa L Krukovskaya
Journal:  Infect Agent Cancer       Date:  2006-12-25       Impact factor: 2.965
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