| Literature DB >> 11703932 |
Abstract
TGF-beta signaling is modulated by Smurfs, E3-ubiquitin ligases that selectively target the receptors and Smad proteins for degradation. New evidence from Drosophila suggests that Smurfs regulate the amplitude and the duration of the cellular response to signaling in vivo.Entities:
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Year: 2001 PMID: 11703932 DOI: 10.1016/s1534-5807(01)00067-3
Source DB: PubMed Journal: Dev Cell ISSN: 1534-5807 Impact factor: 12.270