Literature DB >> 11702647

Features of age-related macular degeneration on optical coherence tomography.

W Van Kerckhoven1, B Lafaut, I Follens, J J De Laey.   

Abstract

PURPOSE: To describe Optical Coherence Tomographic (OCT) findings in age-related macular lesions. PATIENTS AND METHODS: We selected 6 patients with characteristic features of age-related macular disease on OCT, 4 of whom presented with Choroidal New Vessels (CNV). OCT is analogous to ultrasound, except that light is used instead of sound. The reflected light is analysed with the technique of low-coherence interferometry.
RESULTS: Classic CNV present with well-defined boundaries on OCT, whereas occult CNV can present with well- or poorly defined boundaries. Findings in Chronic Central Serous Chorioretinopathy (CSCR) and Adult Onset Vitelliform Dystrophy (AOVD) need angiographic correlation when compared to findings in CNV.
CONCLUSION: OCT cannot replace conventional diagnostic techniques in exsudative Age-related Macular Degeneration. Although it accurately depicts associated changes and especially the associated serous detachment in macular disease, the imaging of neovascular membranes faces limited penetration and resolution. The interpretation of the tomograms requires further clinico-histological correlation.

Entities:  

Mesh:

Year:  2001        PMID: 11702647

Source DB:  PubMed          Journal:  Bull Soc Belge Ophtalmol        ISSN: 0081-0746


  5 in total

1.  Combined use of SLO microperimetry and OCT for retinal functional and structural testing.

Authors:  Marcel N Menke; Eiichi Sato; Frans J Van De Velde; Gilbert T Feke
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2005-08-25       Impact factor: 3.117

Review 2.  Anti-vascular endothelial growth factor for neovascular age-related macular degeneration.

Authors:  Sharon D Solomon; Kristina Lindsley; Satyanarayana S Vedula; Magdalena G Krzystolik; Barbara S Hawkins
Journal:  Cochrane Database Syst Rev       Date:  2014-08-29

3.  Inter-observer agreement for spectral- and time-domain optical coherence tomography image grading: a prospective study.

Authors:  Pascal B Knecht; Helena Kordic; Malaika Kurz-Levin; Veit Sturm; Marcel N Menke
Journal:  Int Ophthalmol       Date:  2012-09-22       Impact factor: 2.031

Review 4.  Antiangiogenic therapy with anti-vascular endothelial growth factor modalities for neovascular age-related macular degeneration.

Authors:  S S Vedula; M G Krzystolik
Journal:  Cochrane Database Syst Rev       Date:  2008-04-16

5.  Anti-vascular endothelial growth factor for neovascular age-related macular degeneration.

Authors:  Sharon D Solomon; Kristina Lindsley; Satyanarayana S Vedula; Magdalena G Krzystolik; Barbara S Hawkins
Journal:  Cochrane Database Syst Rev       Date:  2019-03-04
  5 in total

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