Literature DB >> 11702401

Novel oxindole derivatives and their biological activity.

J Strigácová1, D Hudecová, M Mikulásová, L Varecka, A Lásiková, D Végh.   

Abstract

The antifungal activity of fourteen novel derivatives of oxindole with side chain was studied using representatives of toxinogenic, phytopathogenic and dermatophytic filamentous fungi. Derivatives with exocyclic C=C bond in position C-3 exhibited a higher antifungal activity compared with derivatives with an exocyclic C-C bond in the same position. The strongest antifungal effects were shown by 3-(-2-thienoylmethylidene)-indol-2(3H)-ones.

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Year:  2001        PMID： 11702401     DOI： 10.1007/bf02818531

Source DB:  PubMed          Journal:  Folia Microbiol (Praha)        ISSN： 0015-5632            Impact factor:   2.099


  12 in total

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Journal:  J Med Chem       Date:  1996-01-05       Impact factor: 7.446

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  3 in total

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