Literature DB >> 11701979

Dihydroxyacetone in a new formulation--a powerful therapeutic option in vitiligo.

H Fesq1, K Brockow, K Strom, M Mempel, J Ring, D Abeck.   

Abstract

BACKGROUND: Most treatment protocols for vitiligo require a long treatment duration and usually do not result in complete repigmentation. Therefore, cosmetically acceptable and easily to handle alternatives are warranted.
OBJECTIVE: To evaluate the properties of dihydroxyacetone (DHA) in a new formulation for the treatment of vitiligo on exposed areas.
METHODS: We treated 10 patients suffering from vitiligo affecting the face and/or hands with a newly introduced, commercially available self-bronzing cream containing DHA 5%. DHA was applied every second day.
RESULTS: The characteristic pigmentation showed very satisfactory cosmetic results in 8 out of 10 patients after 2 weeks of treatment.
CONCLUSION: The new DHA formulation is a practical and well-accepted treatment modality. Copyright 2001 S. Karger AG, Basel

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Year:  2001        PMID: 11701979     DOI: 10.1159/000051757

Source DB:  PubMed          Journal:  Dermatology        ISSN: 1018-8665            Impact factor:   5.366


  3 in total

Review 1.  Synthetic Biomaterials from Metabolically Derived Synthons.

Authors:  Nicole G Ricapito; Cynthia Ghobril; Heng Zhang; Mark W Grinstaff; David Putnam
Journal:  Chem Rev       Date:  2016-01-29       Impact factor: 60.622

2.  A hypothesis for examining dihydroxyacetone, the active component in sunless tanning products, as a topical prophylactic against SARS-COV-2 transmission.

Authors:  David M Perrin
Journal:  Med Hypotheses       Date:  2020-09-16       Impact factor: 1.538

3.  A mechanism of covalent substrate binding in the x-ray structure of subunit K of the Escherichia coli dihydroxyacetone kinase.

Authors:  Christian Siebold; Luis Fernando García-Alles; Bernhard Erni; Ulrich Baumann
Journal:  Proc Natl Acad Sci U S A       Date:  2003-06-17       Impact factor: 12.779

  3 in total

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