Literature DB >> 11700750

Limiting the use of gastrointestinal decontamination does not worsen the outcome from deliberate self-poisoning.

M Ardagh1, D Flood, C Tait.   

Abstract

AIM: To review the current epidemiology of patients with deliberate self-poisoning presenting to Christchurch Emergency Department, and to compare this with 1996, 1992, and 1989 data.
METHODS: A retrospective analysis of computer and case records over the twelve-month period of 1999 was conducted and compared with published data from 1996,1992 and 1989.
RESULTS: There were 561 presentations of deliberate self-poisoning to Christchurch Hospital, representing 0.87% of total presentations (compared with 1.1% in 1996, 1.2% in 1992, and 1.0% in 1989). The female to male ratio was 2.2:1.0 (compared with 1.9:1.0, 1.5:1.0, and 2.1:1.0). The principal drugs ingested were antidepressants 30.8% (compared with 20.1%, 24.4%,15.7%), paracetamol 23.5% (compared with 16.7%, 16.9%, 10.6%), benzodiazepines 23.0% (compared with 11.1%, 23.6% 22.8%) and antipsychotics 17.8% (compared with 10.7%, 16.1%, not reported). Gastrointestinal decontamination was performed in only 14.4% of patients (compared with 61%, 73%, 61%). Activated charcoal was given alone in 13.2% (compared with 54%, 46%, 0.4%), activated charcoal and gastric lavage in 0.7% (7%, 26%, 53%), a whole bowel irrigation in 0.5% (not recorded in previous papers). 70.4% were admitted (compared with 69%, 59%, 64%), 7% to intensive care (10.2%, 10.6%, 18%). There were two deaths (compared with 6, 2 and 2).
CONCLUSIONS: Over the time periods studied the drugs ingested and admission rates remain similar, although a large proportion are now being observed in the emergency short stay ward, reducing admission rates to the ward and intensive care. Trends in gastrointestinal decontamination have changed dramatically over the four time periods, but there has been no worsening in the outcome of patients with deliberate self-poisoning.

Entities:  

Mesh:

Substances:

Year:  2001        PMID: 11700750

Source DB:  PubMed          Journal:  N Z Med J        ISSN: 0028-8446


  4 in total

1.  The hazards of gastric lavage for intentional self-poisoning in a resource poor location.

Authors:  Michael Eddleston; Sapumal Haggalla; K Reginald; K Sudarshan; M Senthilkumaran; Lakshman Karalliedde; Ariaranee Ariaratnam; M H Rezvi Sheriff; David A Warrell; Nick A Buckley
Journal:  Clin Toxicol (Phila)       Date:  2007       Impact factor: 4.467

2.  A one-year observational study of all hospitalized acute poisonings in Oslo: complications, treatment and sequelae.

Authors:  Cathrine Lund; Per Drottning; Birgitte Stiksrud; Javad Vahabi; Marianne Lyngra; Ivind Ekeberg; Dag Jacobsen; Knut Erik Hovda
Journal:  Scand J Trauma Resusc Emerg Med       Date:  2012-07-24       Impact factor: 2.953

3.  A Synthetic Receptor as a Specific Antidote for Paraquat Poisoning.

Authors:  Xiangjun Zhang; Xiaoqiu Xu; Shengke Li; Lanlan Li; Jianxiang Zhang; Ruibing Wang
Journal:  Theranostics       Date:  2019-01-21       Impact factor: 11.556

4.  Multiple-dose activated charcoal in acute self-poisoning: a randomised controlled trial.

Authors:  Michael Eddleston; Edmund Juszczak; Nick A Buckley; Lalith Senarathna; Fahim Mohamed; Wasantha Dissanayake; Ariyasena Hittarage; Shifa Azher; K Jeganathan; Shaluka Jayamanne; Mh Rezvi Sheriff; David A Warrell
Journal:  Lancet       Date:  2008-02-16       Impact factor: 79.321

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.