Literature DB >> 11700133

A novel method for the preparation of nucleoside diphosphates.

C L Meyers1, R F Borch.   

Abstract

[reaction--see text] Sugar nucleoside diphosphates have been prepared using an efficient phosphate coupling reaction that employs a highly reactive zwitterionic phosphoramidate intermediate as the phosphorylating species.

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Year:  2001        PMID： 11700133     DOI： 10.1021/ol0167309

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  2 in total

1.  Bisphosphonamidate clodronate prodrug exhibits potent anticancer activity in non-small-cell lung cancer cells.

Authors:  Marie R Webster; Ming Zhao; Michelle A Rudek; Christine L Hann; Caren L Freel Meyers
Journal:  J Med Chem       Date:  2011-09-09       Impact factor: 7.446

2.  Synthesis and biological activity of a gemcitabine phosphoramidate prodrug.

Authors:  Weidong Wu; Jennifer Sigmond; Godefridus J Peters; Richard F Borch
Journal:  J Med Chem       Date:  2007-06-29       Impact factor: 7.446
  2 in total

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