Literature DB >> 11700114

Synthesis of oxime-linked mucin mimics containing the tumor-related T(N) and sialyl T(N) antigens.

L A Marcaurelle1, Y Shin, S Goon, C R Bertozzi.   

Abstract

[reaction--see text] The synthesis of oxime-linked mucin mimics was accomplished via the incorporation of multiple ketone residues into a peptide followed by reaction with aminooxy sugars corresponding to the tumor-related T(N) and sialyl T(N) (ST(N)) antigens.

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Year:  2001        PMID: 11700114     DOI: 10.1021/ol0166247

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  12 in total

1.  Hierarchical assembly of model cell surfaces: synthesis of mucin mimetic polymers and their display on supported bilayers.

Authors:  David Rabuka; Raghuveer Parthasarathy; Goo Soo Lee; Xing Chen; Jay T Groves; Carolyn R Bertozzi
Journal:  J Am Chem Soc       Date:  2007-04-11       Impact factor: 15.419

2.  Hydrolytic stability of hydrazones and oximes.

Authors:  Jeet Kalia; Ronald T Raines
Journal:  Angew Chem Int Ed Engl       Date:  2008       Impact factor: 15.336

3.  Hydrophobic oxime ethers: a versatile class of pDNA and siRNA transfection lipids.

Authors:  Souvik Biswas; Ralph J Knipp; Laura E Gordon; Seshagiri R Nandula; Sven-Ulrik Gorr; Geoffrey J Clark; Michael H Nantz
Journal:  ChemMedChem       Date:  2011-08-31       Impact factor: 3.466

4.  Ketones from Nickel-Catalyzed Decarboxylative, Non-Symmetric Cross-Electrophile Coupling of Carboxylic Acid Esters.

Authors:  Jiang Wang; Brian P Cary; Peyton D Beyer; Samuel H Gellman; Daniel J Weix
Journal:  Angew Chem Int Ed Engl       Date:  2019-07-30       Impact factor: 15.336

5.  Utilization of bench-stable and readily available nickel(II) triflate for access to 1,2-cis-2-aminoglycosides.

Authors:  Eric T Sletten; Sai Kumar Ramadugu; Hien M Nguyen
Journal:  Carbohydr Res       Date:  2016-10-24       Impact factor: 2.104

6.  Nucleophilic cationization reagents.

Authors:  Souvik Biswas; Xuan Huang; Wesley R Badger; Michael H Nantz
Journal:  Tetrahedron Lett       Date:  2010       Impact factor: 2.415

7.  Synthesis of the tumor associative α-aminooxy disaccharide of the TF antigen and its conjugation to a polysaccharide immune stimulant.

Authors:  Jean Paul Bourgault; Kevin R Trabbic; Mengchao Shi; Peter R Andreana
Journal:  Org Biomol Chem       Date:  2014-03-21       Impact factor: 3.876

8.  Noncovalent cell surface engineering: incorporation of bioactive synthetic glycopolymers into cellular membranes.

Authors:  David Rabuka; Martin B Forstner; Jay T Groves; Carolyn R Bertozzi
Journal:  J Am Chem Soc       Date:  2008-04-11       Impact factor: 15.419

9.  Synthesis and microcontact printing of dual end-functionalized mucin-like glycopolymers for microarray applications.

Authors:  Kamil Godula; David Rabuka; Ki Tae Nam; Carolyn R Bertozzi
Journal:  Angew Chem Int Ed Engl       Date:  2009       Impact factor: 15.336

10.  Density variant glycan microarray for evaluating cross-linking of mucin-like glycoconjugates by lectins.

Authors:  Kamil Godula; Carolyn R Bertozzi
Journal:  J Am Chem Soc       Date:  2012-09-12       Impact factor: 15.419

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