| Literature DB >> 11699965 |
V A Mbayed1, L Barbini, J L López, R H Campos.
Abstract
Seven human hepatitis B virus (HBV) genotypes have been described. Genotype F, indigenous to the Americas, is the most diverging group. Our in-depth analysis of the genetic distances of this genotype included ten Argentine samples. Phylogenetic analysis on the small (S) gene of the surface antigen showed four different clusters within genotype F, which were associated with a well-defined geographical origin. Even closely connected sequences sharing a common ancestor had shown some characteristics or markers indicating geographical differentiation. Nucleotide sequences and amino acids translated according to the polymerase open reading frame (P-ORF), rather than S-ORF, yielded a more discriminating analysis.Entities:
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Year: 2001 PMID: 11699965 DOI: 10.1007/s007050170066
Source DB: PubMed Journal: Arch Virol ISSN: 0304-8608 Impact factor: 2.574