Literature DB >> 11699801

Methylphenidate effects on task-switching performance in attention-deficit/hyperactivity disorder.

A F Kramer1, N J Cepeda, M L Cepeda.   

Abstract

OBJECTIVE: To examine the specificity of methylphenidate effects on the processes that support the ability to rapidly and accurately coordinate the performance of multiple tasks in children with attention-deficit hyperactivity disorder (ADHD).
METHOD: Twenty children with ADHD performed the task-switching paradigm while on and off medication. The paradigm involves switching between two different tasks, discriminating the value of a number presented on a computer screen and deciding how many numbers were present on the screen. The children also performed single-task control conditions.
RESULTS: Analyses of variance indicated the medication selectively enhanced the children's ability to rapidly and accurately switch between tasks and to focus attention on the currently relevant response set.
CONCLUSIONS: This study helps to elucidate the nature of methylphenidate effects on the cognitive processes which support the ability to coordinate the performance of multiple tasks. Medication appears to selectively enhance inhibitory processes which support task-switching.

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Year:  2001        PMID: 11699801     DOI: 10.1097/00004583-200111000-00007

Source DB:  PubMed          Journal:  J Am Acad Child Adolesc Psychiatry        ISSN: 0890-8567            Impact factor:   8.829


  17 in total

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9.  Can task-switching training enhance executive control functioning in children with attention deficit/-hyperactivity disorder?

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Review 10.  Methylphenidate for attention deficit hyperactivity disorder (ADHD) in children and adolescents - assessment of adverse events in non-randomised studies.

Authors:  Ole Jakob Storebø; Nadia Pedersen; Erica Ramstad; Maja Lærke Kielsholm; Signe Sofie Nielsen; Helle B Krogh; Carlos R Moreira-Maia; Frederik L Magnusson; Mathilde Holmskov; Trine Gerner; Maria Skoog; Susanne Rosendal; Camilla Groth; Donna Gillies; Kirsten Buch Rasmussen; Dorothy Gauci; Morris Zwi; Richard Kirubakaran; Sasja J Håkonsen; Lise Aagaard; Erik Simonsen; Christian Gluud
Journal:  Cochrane Database Syst Rev       Date:  2018-05-09
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