Literature DB >> 11698650

Degeneracy and complexity in biological systems.

G M Edelman1, J A Gally.   

Abstract

Degeneracy, the ability of elements that are structurally different to perform the same function or yield the same output, is a well known characteristic of the genetic code and immune systems. Here, we point out that degeneracy is a ubiquitous biological property and argue that it is a feature of complexity at genetic, cellular, system, and population levels. Furthermore, it is both necessary for, and an inevitable outcome of, natural selection.

Mesh：

Year:  2001        PMID： 11698650      PMCID： PMC61115          DOI： 10.1073/pnas.231499798

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  47 in total

1.  Measures of degeneracy and redundancy in biological networks.

Authors:  G Tononi; O Sporns; G M Edelman
Journal:  Proc Natl Acad Sci U S A       Date:  1999-03-16       Impact factor: 11.205

2.  Complexity in biological signaling systems.

Authors:  G Weng; U S Bhalla; R Iyengar
Journal:  Science       Date:  1999-04-02       Impact factor: 47.728

3.  The stability of human beta-globin mRNA is dependent on structural determinants positioned within its 3' untranslated region.

Authors:  J E Russell; S A Liebhaber
Journal:  Blood       Date:  1996-06-15       Impact factor: 22.113

Review 4.  A multiplicity of mediators: alternative forms of transcription complexes communicate with transcriptional regulators.

Authors:  M Chang; J A Jaehning
Journal:  Nucleic Acids Res       Date:  1997-12-15       Impact factor: 16.971

5.  A complexity measure for selective matching of signals by the brain.

Authors:  G Tononi; O Sporns; G M Edelman
Journal:  Proc Natl Acad Sci U S A       Date:  1996-04-16       Impact factor: 11.205

Review 6.  Structural and functional specificity of FGF receptors.

Authors:  J Partanen; S Vainikka; K Alitalo
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1993-06-29       Impact factor: 6.237

7.  MGA2 or SPT23 is required for transcription of the delta9 fatty acid desaturase gene, OLE1, and nuclear membrane integrity in Saccharomyces cerevisiae.

Authors:  S Zhang; Y Skalsky; D J Garfinkel
Journal:  Genetics       Date:  1999-02       Impact factor: 4.562

8.  Two copies of a subelement from the Vg1 RNA localization sequence are sufficient to direct vegetal localization in Xenopus oocytes.

Authors:  D Gautreau; C A Cote; K L Mowry
Journal:  Development       Date:  1997-12       Impact factor: 6.868

9.  Myogenin can substitute for Myf5 in promoting myogenesis but less efficiently.

Authors:  Y Wang; R Jaenisch
Journal:  Development       Date:  1997-07       Impact factor: 6.868

10.  Redundant enhancer elements guide beta 1 tubulin gene expression in apodemes during Drosophila embryogenesis.

Authors:  D Buttgereit
Journal:  J Cell Sci       Date:  1993-07       Impact factor: 5.285
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  296 in total

1.  Naturalizing consciousness: a theoretical framework.

Authors:  Gerald M Edelman
Journal:  Proc Natl Acad Sci U S A       Date:  2003-04-17       Impact factor: 11.205

2.  Multiple models to capture the variability in biological neurons and networks.

Authors:  Eve Marder; Adam L Taylor
Journal:  Nat Neurosci       Date:  2011-02       Impact factor: 24.884

Review 3.  The ribosome filter hypothesis.

Authors:  Vincent P Mauro; Gerald M Edelman
Journal:  Proc Natl Acad Sci U S A       Date:  2002-09-09       Impact factor: 11.205

Review 4.  Control of male gametophyte development.

Authors:  Sheila McCormick
Journal:  Plant Cell       Date:  2004-03-22       Impact factor: 11.277

5.  Macrophyte species drive the variation of bacterioplankton community composition in a shallow freshwater lake.

Authors:  Jin Zeng; Yuanqi Bian; Peng Xing; Qinglong L Wu
Journal:  Appl Environ Microbiol       Date:  2011-10-28       Impact factor: 4.792

6.  Animal-to-animal variability of connection strength in the leech heartbeat central pattern generator.

Authors:  Rebecca C Roffman; Brian J Norris; Ronald L Calabrese
Journal:  J Neurophysiol       Date:  2011-12-21       Impact factor: 2.714

7.  Sports teams as superorganisms: implications of sociobiological models of behaviour for research and practice in team sports performance analysis.

Authors:  Ricardo Duarte; Duarte Araújo; Vanda Correia; Keith Davids
Journal:  Sports Med       Date:  2012-08-01       Impact factor: 11.136

8.  It's all connected: Pathways in visual object recognition and early noun learning.

Authors:  Linda B Smith
Journal:  Am Psychol       Date:  2013-11

9.  Distinct neural correlates of episodic memory among apolipoprotein E alleles in cognitively normal elderly.

Authors:  Hao Shu; Yongmei Shi; Gang Chen; Zan Wang; Duan Liu; Chunxian Yue; B Douglas Ward; Wenjun Li; Zhan Xu; Guangyu Chen; Qi-Hao Guo; Jun Xu; Shi-Jiang Li; Zhijun Zhang
Journal:  Brain Imaging Behav       Date:  2019-02       Impact factor: 3.978

10.  Visuo-postural adaptation during the acquisition of a visually guided weight-shifting task: age-related differences in global and local dynamics.

Authors:  Vassilia Hatzitaki; Stylianos Konstadakos
Journal:  Exp Brain Res       Date:  2007-06-19       Impact factor: 1.972
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