Literature DB >> 11695390

Cutaneous leishmaniasis infection in Balb/c mice using a Leishmania tropica strain isolated from Turkey.

N Girginkardeşler1, I C Balcioğlu, K Yereli, A Ozbilgin, Y Ozbel.   

Abstract

Leishmania tropica, which is endemic in Turkey, is the causative agent of cutaneous leishmaniasis. Leishmania tropica promastigotes (2 x 10(7)) isolated from a patient with dermal leishmaniasis and reproduced in NNN medium were inoculated subcutaneously into the footpads of 10 Balb/c mice. Cutaneous leishmaniasis developed on the footpads of 4 mice approximately 45 days later. Leishmania tropica amastigotes were observed in smear slides and then cultivated in NNN medium. Balb/c mice are a suitable laboratory model for this isolate of L. tropica and thus a source of amastigotes for studies on the immunology, chemotherapy, and pathogenicity of cutaneous leishmaniasis.

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Year:  2001        PMID： 11695390     DOI： 10.1645/0022-3395(2001)087[1177:CLIIBC]2.0.CO;2

Source DB:  PubMed          Journal:  J Parasitol        ISSN： 0022-3395            Impact factor:   1.276


  4 in total

1.  Genetics of host response to Leishmania tropica in mice - different control of skin pathology, chemokine reaction, and invasion into spleen and liver.

Authors:  Tetyana Kobets; Helena Havelková; Igor Grekov; Valeriya Volkova; Jarmila Vojtíšková; Martina Slapničková; Iryna Kurey; Yahya Sohrabi; Milena Svobodová; Peter Demant; Marie Lipoldová
Journal:  PLoS Negl Trop Dis       Date:  2012-06-05

2.  Mapping the genes for susceptibility and response to Leishmania tropica in mouse.

Authors:  Yahya Sohrabi; Helena Havelková; Tetyana Kobets; Matyáš Šíma; Valeriya Volkova; Igor Grekov; Taťána Jarošíková; Iryna Kurey; Jarmila Vojtíšková; Milena Svobodová; Peter Demant; Marie Lipoldová
Journal:  PLoS Negl Trop Dis       Date:  2013-07-11

3.  Development of a Murine Infection Model with Leishmania killicki, Responsible for Cutaneous Leishmaniosis in Algeria: Application in Pharmacology.

Authors:  Naouel Eddaikra; Ihcene Kherachi Djenad; Sihem Benbetka; Razika Benikhlef; Khatima Aït-Oudhia; Farida Moulti-Mati; Bruno Oury; Denis Sereno; Zoubir Harrat
Journal:  Biomed Res Int       Date:  2016-02-02       Impact factor: 3.411

4.  Vaccination with whole-cell killed or recombinant leishmanial protein and toll-like receptor agonists against Leishmania tropica in BALB/c mice.

Authors:  Mosayeb Rostamian; Fariborz Bahrami; Hamid M Niknam
Journal:  PLoS One       Date:  2018-09-24       Impact factor: 3.240
  4 in total

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