Literature DB >> 11694798

The treatment of cerebrospinal fluid shunt infections. Results from a practice survey of the American Society of Pediatric Neurosurgeons.

W E Whitehead1, J R Kestle.   

Abstract

It is our impression that the management strategy for infected cerebrospinal fluid (CSF) shunts varies significantly among pediatric neurosurgeons. The purpose of this paper is to present the results of a practice survey on the treatment of shunt infections which was distributed to all active members of the American Society of Pediatric Neurosurgeons (ASPN). Eighty-four of 129 ASPN members (65%) responded to the survey. Most ASPN members remove the shunt and place an external ventricular drain (EVD) to treat Staphylococcus epidermidis (59.5%), S. aureus (64.3%) and gram-negative rod infections (67.9%). The second most common method of treatment was externalization of the shunt (33.3, 29.8 and 25%, respectively). The duration of antibiotic treatment was extremely variable. When the shunt was removed and an EVD inserted, the duration of antibiotic treatment for S. epidermidis and S. aureus ranged from 5 to 21 total days (2-21 days of sterile cultures). For gram-negative rod infections treated with shunt removal and an EVD, the total duration of antibiotic therapy ranged from 5 to 24 days (2-37 days of sterile cultures). The majority of ASPN members remove the infected CSF shunt and place an EVD for the management of shunt infections. Significant variation exists in the duration of antibiotic therapy. Determining the most effective duration of antibiotic therapy in an effort to shorten hospitalization and minimize complications without sacrificing efficacy will require further study. Copyright 2001 S. Karger AG, Basel

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Year:  2001        PMID: 11694798     DOI: 10.1159/000050422

Source DB:  PubMed          Journal:  Pediatr Neurosurg        ISSN: 1016-2291            Impact factor:   1.162


  23 in total

Review 1.  Strategies to decrease the risk of ventricular catheter infections: a review of the evidence.

Authors:  Maya A Babu; Robin Patel; W Richard Marsh; Eelco F M Wijdicks
Journal:  Neurocrit Care       Date:  2012-02       Impact factor: 3.210

Review 2.  Cerebrospinal fluid diversion devices and infection. A comprehensive review.

Authors:  R Gutiérrez-González; G R Boto; A Pérez-Zamarrón
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2011-09-30       Impact factor: 3.267

3.  Prophylactic antibiotics in pediatric shunt surgery.

Authors:  N Biyani; G Grisaru-Soen; P Steinbok; S Sgouros; S Constantini
Journal:  Childs Nerv Syst       Date:  2006-05-18       Impact factor: 1.475

4.  Few Patient, Treatment, and Diagnostic or Microbiological Factors, Except Complications and Intermittent Negative Cerebrospinal Fluid (CSF) Cultures During First CSF Shunt Infection, Are Associated With Reinfection.

Authors:  Tamara D Simon; Nicole Mayer-Hamblett; Kathryn B Whitlock; Marcie Langley; John R W Kestle; Jay Riva-Cambrin; Margaret Rosenfeld; Emily A Thorell
Journal:  J Pediatric Infect Dis Soc       Date:  2013-08-26       Impact factor: 3.164

Review 5.  Shunt infections: a review and analysis of a personal series.

Authors:  Santosh Mohan Rao Kanangi; Chidambaram Balasubramaniam
Journal:  Childs Nerv Syst       Date:  2018-07-05       Impact factor: 1.475

6.  A standardized protocol to reduce cerebrospinal fluid shunt infection: the Hydrocephalus Clinical Research Network Quality Improvement Initiative.

Authors:  John R W Kestle; Jay Riva-Cambrin; John C Wellons; Abhaya V Kulkarni; William E Whitehead; Marion L Walker; W Jerry Oakes; James M Drake; Thomas G Luerssen; Tamara D Simon; Richard Holubkov
Journal:  J Neurosurg Pediatr       Date:  2011-07       Impact factor: 2.375

7.  Microbiology and treatment of cerebrospinal fluid shunt infections in children.

Authors:  Daniel J Adams; Michael Rajnik
Journal:  Curr Infect Dis Rep       Date:  2014-10       Impact factor: 3.725

8.  Reinfection after treatment of first cerebrospinal fluid shunt infection: a prospective observational cohort study.

Authors:  Tamara D Simon; Matthew P Kronman; Kathryn B Whitlock; Nancy E Gove; Nicole Mayer-Hamblett; Samuel R Browd; D Douglas Cochrane; Richard Holubkov; Abhaya V Kulkarni; Marcie Langley; David D Limbrick; Thomas G Luerssen; W Jerry Oakes; Jay Riva-Cambrin; Curtis Rozzelle; Chevis Shannon; Mandeep Tamber; John C Wellons; William E Whitehead; John R W Kestle
Journal:  J Neurosurg Pediatr       Date:  2018-02-02       Impact factor: 2.375

9.  Initial experience with antibiotic-impregnated silicone catheters for shunting of cerebrospinal fluid in children.

Authors:  Henry E Aryan; Hal S Meltzer; Min S Park; Rebecca L Bennett; Rahul Jandial; Michael L Levy
Journal:  Childs Nerv Syst       Date:  2004-10-12       Impact factor: 1.475

10.  Variability in Management of First Cerebrospinal Fluid Shunt Infection: A Prospective Multi-Institutional Observational Cohort Study.

Authors:  Tamara D Simon; Matthew P Kronman; Kathryn B Whitlock; Nancy Gove; Samuel R Browd; Richard Holubkov; John R W Kestle; Abhaya V Kulkarni; Marcie Langley; David D Limbrick; Thomas G Luerssen; Jerry Oakes; Jay Riva-Cambrin; Curtis Rozzelle; Chevis Shannon; Mandeep Tamber; John C Wellons; William E Whitehead; Nicole Mayer-Hamblett
Journal:  J Pediatr       Date:  2016-09-28       Impact factor: 4.406

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