Literature DB >> 1169097

Diarrhoeae in thyroid medullary carcinoma: role of prostaglandins and therapeutic effect of nutmeg.

J A Barrowman, A Bennett, P Hillenbrand, K Rolles, D J Pollock, J T Wright.   

Abstract

In a patient with medullary carcinoma of the thyroid with pulmonary metastases who presented with diarrhoea and steatorrhoea large amounts of prostaglandin-like material were present in peripheral blood, and some was extracted from the tumour. The diarrhoea which persisted after thyroidectomy responded to treatment with nutmeg.

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Year:  1975        PMID： 1169097      PMCID： PMC1673758          DOI： 10.1136/bmj.3.5974.11

Source DB:  PubMed          Journal:  Br Med J        ISSN： 0007-1447


  14 in total

1.  ON THE PRESENCE OF A SECOND SPECIFIC CELL SYSTEM IN MAMMALIAN THYROID GLAND.

Authors:  B FALCK; B LARSON; E ROSENGREN; K SVENAEUS
Journal:  Acta Physiol Scand       Date:  1964-12

2.  The cytochemistry of the thyroid C cells and their relationship to calcitonin.

Authors:  A G Pearse
Journal:  Proc R Soc Lond B Biol Sci       Date:  1966-04-19

3.  Prostaglandin secretion by medullary carcinoma of the thyroid. A possible cause of the associated idarrhoea.

Authors:  E D Williams; S M Karim; M Sandler
Journal:  Lancet       Date:  1968-01-06       Impact factor: 79.321

4.  Nutmeg for diarrhea of medullary carcinoma of thyroid.

Authors:  W N Fawell; G Thompson
Journal:  N Engl J Med       Date:  1973-07-12       Impact factor: 91.245

Review 5.  Prostaglandins and the gastrointestinal tract.

Authors:  A Bennett; B Fleshler
Journal:  Gastroenterology       Date:  1970-11       Impact factor: 22.682

6.  Letter: Prostaglandins, nutmeg and diarrhea.

Authors:  A Bennett; C F Gradidge; I F Stamford
Journal:  N Engl J Med       Date:  1974-01-10       Impact factor: 91.245

7.  Elevated histaminase activity in medullary carcinoma of the thyroid gland.

Authors:  S B Baylin; M A Beaven; K Engelman; A Sjoerdsma
Journal:  N Engl J Med       Date:  1970-12-03       Impact factor: 91.245

8.  Extraction of prostaglandins from human blood.

Authors:  W G Unger; I F Stamford; A Bennett
Journal:  Nature       Date:  1971-10-01       Impact factor: 49.962

9.  Prostaglandin E2 and gastric acid secretion in man.

Authors:  A Bennett; I F Stamford; W G Unger
Journal:  J Physiol       Date:  1973-03       Impact factor: 5.182

10.  Diarrhoea associated with medullary carcinoma of the thyroid.

Authors:  J J Bernier; J C Rambaud; D Cattan; A Prost
Journal:  Gut       Date:  1969-12       Impact factor: 23.059
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  8 in total

Review 1.  The C cells (parafollicular cells) of the thyroid gland and medullary thyroid carcinoma. A review.

Authors:  J B Hazard
Journal:  Am J Pathol       Date:  1977-07       Impact factor: 4.307

2.  Bradshaw lecture, 1976. Thyroid medullary carcinoma.

Authors:  S Taylor
Journal:  Ann R Coll Surg Engl       Date:  1977-09       Impact factor: 1.891

3.  Pathophysiological study of diarrhoea in a patient with medullary thyroid carcinoma. Evidence against a secretory mechanism and for the role of shortened colonic transit time.

Authors:  J C Rambaud; R Jian; B Flourié; M Hautefeuille; M Salmeron; F Thuillier; A Ruskoné; C Florent; F Chaoui; J J Bernier
Journal:  Gut       Date:  1988-04       Impact factor: 23.059

4.  Inaugural Sidney Werner Lecture. The surgical treatment of thyroid disease in modern perspective.

Authors:  S Taylor
Journal:  Ann R Coll Surg Engl       Date:  1979-03       Impact factor: 1.891

5.  Medullary carcinoma of the thyroid.

Authors:  J Lynn; O I Gamvros; S Taylor
Journal:  World J Surg       Date:  1981-01       Impact factor: 3.352

Review 6.  Multiple endocrine neoplasia syndromes.

Authors:  A Pont
Journal:  West J Med       Date:  1980-04

Review 7.  Prostaglandins and serotonin: nonpeptide diarrheogenic hormones.

Authors:  B M Jaffe
Journal:  World J Surg       Date:  1979-09-20       Impact factor: 3.352

Review 8.  Potential therapeutic applications of aspirin and other cyclo-oxygenase inhibitors.

Authors:  A E Farah; F Rosenberg
Journal:  Br J Clin Pharmacol       Date:  1980-10       Impact factor: 4.335
  8 in total

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