AIM: A randomised, controlled, double-blind, clinical trial was conducted to investigate the effect of a chlorhexidine acetate/xylitol gum (ACHX) on the plaque and gingival indices of 111 elderly occupants in residential homes. A gum containing xylitol alone (X) and a no gum (N) group was included. Participants' opinions about chewing gum were also investigated. METHODS: Subjects chewed 2 pellets, for 15 min, 2x daily for 12 months. RESULTS: In the ACHX group, the plaque and gingival indices significantly decreased (p<0.001) over the 12 months. In the X group, only the plaque score significantly decreased (p<0.05) and in the N control group, both indices remained high and did not change significantly. The acceptance of both chewing gums was high but more participants in the ACHX group felt that the gum kept their mouth healthy (p<0.05). The effect of the ACHX gum on plaque and gingival indices was significantly greater than for the X gum. CONCLUSION: The long-term use of a chlorhexidine acetate/xylitol chewing gum may therefore support oral hygiene routines for an elderly dependent population.
RCT Entities:
AIM: A randomised, controlled, double-blind, clinical trial was conducted to investigate the effect of a chlorhexidine acetate/xylitol gum (ACHX) on the plaque and gingival indices of 111 elderly occupants in residential homes. A gum containing xylitol alone (X) and a no gum (N) group was included. Participants' opinions about chewing gum were also investigated. METHODS: Subjects chewed 2 pellets, for 15 min, 2x daily for 12 months. RESULTS: In the ACHX group, the plaque and gingival indices significantly decreased (p<0.001) over the 12 months. In the X group, only the plaque score significantly decreased (p<0.05) and in the N control group, both indices remained high and did not change significantly. The acceptance of both chewing gums was high but more participants in the ACHX group felt that the gum kept their mouth healthy (p<0.05). The effect of the ACHX gum on plaque and gingival indices was significantly greater than for the X gum. CONCLUSION: The long-term use of a chlorhexidine acetate/xylitol chewing gum may therefore support oral hygiene routines for an elderly dependent population.
Authors: Henry Daniell; Smruti K Nair; Hancheng Guan; Yuwei Guo; Rachel J Kulchar; Marcelo D T Torres; Md Shahed-Al-Mahmud; Geetanjali Wakade; Yo-Min Liu; Andrew D Marques; Jevon Graham-Wooten; Wan Zhou; Ping Wang; Sudheer K Molugu; William R de Araujo; Cesar de la Fuente-Nunez; Che Ma; William R Short; Pablo Tebas; Kenneth B Margulies; Frederic D Bushman; Francis K Mante; Robert P Ricciardi; Ronald G Collman; Mark S Wolff Journal: Biomaterials Date: 2022-07-18 Impact factor: 15.304
Authors: Adam L Gordon; Phillipa A Logan; Rob G Jones; Calum Forrester-Paton; Jonathan P Mamo; John R F Gladman Journal: BMC Geriatr Date: 2012-06-25 Impact factor: 3.921
Authors: Melanie Nasseripour; Jonathon Timothy Newton; Fiona Warburton; Oluwatunmise Awojobi; Sonya Di Giorgio; Jennifer Elizabeth Gallagher; Avijit Banerjee Journal: Front Oral Health Date: 2022-03-30