| Literature DB >> 11686006 |
B J Van Lenten1, M Navab, D Shih, A M Fogelman, A J Lusis.
Abstract
High-density lipoproteins (HDL) in the basal state are anti-inflammatory, capable of destroying oxidized lipids that generate an inflammatory response. However, HDL during acute inflammation are altered and become pro-inflammatory. This "chameleon-like" nature of HDL is considered to be due to the complex composition of HDL. The data reviewed here demonstrate the key role of HDL in modulating inflammation and its implications for atherogenesis.Entities:
Mesh：
Substances：
Year: 2001 PMID： 11686006 DOI： 10.1016/s1050-1738(01)00095-0
Source DB: PubMed Journal: Trends Cardiovasc Med ISSN： 1050-1738 Impact factor: 6.677