Literature DB >> 11684436

The interplay between Mad and Myc in proliferation and differentiation.

Z Q Zhou1, P J Hurlin.   

Abstract

Members of the Myc family of transcription factors are key regulators of cell proliferation, and excessive levels of Myc lead to tumor formation. Mad family proteins are related to Myc, but they antagonize the oncogenic activity of Myc in cell-culture assays. Here, we examine current models of Mad function and the relationship between Mad and Myc in cell proliferation, differentiation and tumorigenesis.

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Year:  2001        PMID： 11684436     DOI： 10.1016/s0962-8924(01)02121-3

Source DB:  PubMed          Journal:  Trends Cell Biol        ISSN： 0962-8924            Impact factor:   20.808


  26 in total

1.  Functional analysis of the Mad1-mSin3A repressor-corepressor interaction reveals determinants of specificity, affinity, and transcriptional response.

Authors:  Shaun M Cowley; Richard S Kang; John V Frangioni; Jason J Yada; Alec M DeGrand; Ishwar Radhakrishnan; Robert N Eisenman
Journal:  Mol Cell Biol       Date:  2004-04       Impact factor: 4.272

2.  Sequence signatures and the probabilistic identification of proteins in the Myc-Max-Mad network.

Authors:  William R Atchley; Andrew D Fernandes
Journal:  Proc Natl Acad Sci U S A       Date:  2005-04-25       Impact factor: 11.205

3.  Inflammatory disease and lymphomagenesis caused by deletion of the Myc antagonist Mnt in T cells.

Authors:  Shala Dezfouli; Antony Bakke; Jie Huang; Anthony Wynshaw-Boris; Peter J Hurlin
Journal:  Mol Cell Biol       Date:  2006-03       Impact factor: 4.272

4.  c-Myc depletion inhibits proliferation of human tumor cells at various stages of the cell cycle.

Authors:  H Wang; S Mannava; V Grachtchouk; D Zhuang; M S Soengas; A V Gudkov; E V Prochownik; M A Nikiforov
Journal:  Oncogene       Date:  2007-10-01       Impact factor: 9.867

5.  Whole-genome analysis reveals a strong positional bias of conserved dMyc-dependent E-boxes.

Authors:  Toby Hulf; Paola Bellosta; Michael Furrer; Dominik Steiger; David Svensson; Andrew Barbour; Peter Gallant
Journal:  Mol Cell Biol       Date:  2005-05       Impact factor: 4.272

6.  Deletion of Mnt leads to disrupted cell cycle control and tumorigenesis.

Authors:  Peter J Hurlin; Zi-Qiang Zhou; Kazuhito Toyo-oka; Sara Ota; William L Walker; Shinji Hirotsune; Anthony Wynshaw-Boris
Journal:  EMBO J       Date:  2003-09-15       Impact factor: 11.598

7.  Kinetic analysis of genomewide gene expression reveals molecule circuitries that control T cell activation and Th1/2 differentiation.

Authors:  Binfeng Lu; Panayiotis Zagouras; James E Fischer; Junfeng Lu; Baiyong Li; Richard A Flavell
Journal:  Proc Natl Acad Sci U S A       Date:  2004-02-20       Impact factor: 11.205

8.  Mad3 negatively regulates B cell differentiation in the spleen by inducing Id2 expression.

Authors:  Yael Gore; Frida Lantner; Gili Hart; Idit Shachar
Journal:  Mol Biol Cell       Date:  2010-04-07       Impact factor: 4.138

9.  A novel role of the Mad family member Mad3 in cerebellar granule neuron precursor proliferation.

Authors:  Jun-Soo Yun; Jennifer M Rust; Tatsuto Ishimaru; Elva Díaz
Journal:  Mol Cell Biol       Date:  2007-09-24       Impact factor: 4.272

10.  Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network.

Authors:  Amir Orian; Bas van Steensel; Jeffrey Delrow; Harmen J Bussemaker; Ling Li; Tomoyuki Sawado; Eleanor Williams; Lenora W M Loo; Shaun M Cowley; Cynthia Yost; Sarah Pierce; Bruce A Edgar; Susan M Parkhurst; Robert N Eisenman
Journal:  Genes Dev       Date:  2003-04-14       Impact factor: 11.361
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