D Kaye1. 1. Department of Obstetrics and Gynaecology, Makerere University Medical School, P.O. Box 7072, Kampala, Uganda.
Abstract
OBJECTIVE: To evaluate the epidemiological risk factors in patients admitted at Mulago Hospital with preterm premature rupture of the membranes from their socio-demographic characteristics and reproductive history. DESIGN: Cross-sectional case control study. SETTING: Labour ward, Mulago Hospital, Kampala, Uganda. METHODS: Cases were enrolled at admission while controls were enrolled after a term delivery not preceded by pre-mature rupture of the membrane (PROM). Controls were matched for age range (age +/- 2 years) and parity with the cases. A detailed history of socio-demographic characteristics, past medical and surgical illness and past reproductive history were obtained and data entered into a coded questionnaire. Endocervical swabs and amniotic fluid samples were taken from the cases during labour. Validity was assessed using Chi-square with a p-value of less than 0.05 considered significant. RESULTS: Maternal socio-demographic characteristics were similar for cases and controls. A history of hypertension, abortion, prior PROM, Caesarean section, cervical cerclage, cervical incompetence or abnormal vaginal discharge were significant risk factors for preterm PROM (p < 0.05). CONCLUSION: There are factors by which mothers at risk of preterm PROM can be identified before onset of rupture.
OBJECTIVE: To evaluate the epidemiological risk factors in patients admitted at Mulago Hospital with preterm premature rupture of the membranes from their socio-demographic characteristics and reproductive history. DESIGN: Cross-sectional case control study. SETTING: Labour ward, Mulago Hospital, Kampala, Uganda. METHODS: Cases were enrolled at admission while controls were enrolled after a term delivery not preceded by pre-mature rupture of the membrane (PROM). Controls were matched for age range (age +/- 2 years) and parity with the cases. A detailed history of socio-demographic characteristics, past medical and surgical illness and past reproductive history were obtained and data entered into a coded questionnaire. Endocervical swabs and amniotic fluid samples were taken from the cases during labour. Validity was assessed using Chi-square with a p-value of less than 0.05 considered significant. RESULTS: Maternal socio-demographic characteristics were similar for cases and controls. A history of hypertension, abortion, prior PROM, Caesarean section, cervical cerclage, cervical incompetence or abnormal vaginal discharge were significant risk factors for preterm PROM (p < 0.05). CONCLUSION: There are factors by which mothers at risk of preterm PROM can be identified before onset of rupture.