Literature DB >> 1168097

Nuclear magnetic resonance investigations of human neoplastic and abnormal nonneoplastic tissues.

J C Eggleston, L A Saryan, D P Hollis.   

Abstract

A large number of samples of human neoplastic and abnormal nonneoplastic tissues were studied by nuclear magnetic resonance spectrometry in order to evaluate the possible role of this technique in the diagnosis of cancer. The spin-lattice magnetic relaxation times (T1) of abnormal nonneoplastic tissue were longer, in many instances, than those of malignant tumors from similar sites, preventing recognition of the tumors in this manner. The evidence for the nonspecific nature of the prolongation of T1 in abnormal tissue is reviewed, and additional limitations of this technique in the diagnosis of cancer are indicated.

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Year:  1975        PMID: 1168097

Source DB:  PubMed          Journal:  Cancer Res        ISSN: 0008-5472            Impact factor:   12.701


  11 in total

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3.  Proton T1 study of coverage parameter changes in tissues from tumor-bearing mice.

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4.  Magnetic resonance imaging versus computed tomography in the evaluation of soft tissue tumors of the extremities.

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6.  Glial tumoral proliferation induces changes in the state and physical properties of water during ENU-induction of brain tumors in rats.

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7.  Nuclear magnetic resonance in cancer, XII: Application of NMR malignancy index to human lung tumours.

Authors:  M Goldsmith; J A Koutcher; R Damadian
Journal:  Br J Cancer       Date:  1977-08       Impact factor: 7.640

8.  Changes in NMR relaxation times of adjacent muscle after implantation of malignant and normal tissue.

Authors:  C R Ling; M A Foster; J R Mallard
Journal:  Br J Cancer       Date:  1979-12       Impact factor: 7.640

9.  NMR in cancer, XIII: application of the NMR malignancy index to human mammary tumours.

Authors:  M Goldsmith; J A Koutcher; R Damadian
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10.  NMR investigation of experimental chemical induced brain tumors in rats, potential of a superparamagnetic contrast agent (MD3) to improve diagnosis.

Authors:  V Rousseau; D Pouliquen; F Darcel; P Jallet; J J Le Jeune
Journal:  MAGMA       Date:  1998-08       Impact factor: 2.533

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