Literature DB >> 11679201

The antioxidant effect of free bilirubin on cumene-hydroperoxide treated human leukocytes.

A Yesilkaya1, R Altinayak, D K Korgun.   

Abstract

To examine the antioxidant effect of bilirubin (BR) on leukocyte, we treated leukocytes obtained from healthy subjects with an oxidant and various concentrations of BR. High concentrations of BR decreased thiobarbituric acid reactive substances (TBARS) and catalase activities, increased superoxide dismutase (SOD) activity, but had no effect on glutathione (GSH) concentration. Our results showed that under physiological conditions, BR has an antioxidant effect only in high concentrations.

Entities:  

Mesh：

Substances：

Year:  2000        PMID： 11679201     DOI： 10.1016/s0306-3623(01)00084-2

Source DB:  PubMed          Journal:  Gen Pharmacol        ISSN： 0306-3623


  5 in total

1.  Analysis of intestinal haem-oxygenase-1 (HO-1) in clinical and experimental colitis.

Authors:  G Paul; F Bataille; F Obermeier; J Bock; F Klebl; U Strauch; D Lochbaum; P Rümmele; S Farkas; J Schölmerich; M Fleck; G Rogler; H Herfarth
Journal:  Clin Exp Immunol       Date:  2005-06       Impact factor: 4.330

2.  (GT)N dinucleotide repeat polymorphism of haem oxygenase-1 promotor region is not associated with inflammatory bowel disease risk or disease course.

Authors:  M Hausmann; G Paul; S Kellermeier; I Frey; J Schölmerich; W Falk; K Menzel; M Fried; H Herfarth; G Rogler
Journal:  Clin Exp Immunol       Date:  2008-05-05       Impact factor: 4.330

3.  Spatial monitoring of toxicity in HMOX-LacZ transgenic mice.

Authors:  Rachel Young; C Roland Wolf; Ken Brown; John D Hayes; C Bruce A Whitelaw
Journal:  Transgenic Res       Date:  2010-01-14       Impact factor: 2.788

Review 4.  Heme oxygenase-1 and carbon monoxide in pulmonary medicine.

Authors:  Dirk-Jan Slebos; Stefan W Ryter; Augustine M K Choi
Journal:  Respir Res       Date:  2003-08-07

5.  Pleiotropic effect of the proton pump inhibitor esomeprazole leading to suppression of lung inflammation and fibrosis.

Authors:  Yohannes T Ghebremariam; John P Cooke; William Gerhart; Carol Griego; Jeremy B Brower; Melanie Doyle-Eisele; Benjamin C Moeller; Qingtao Zhou; Lawrence Ho; Joao de Andrade; Ganesh Raghu; Leif Peterson; Andreana Rivera; Glenn D Rosen
Journal:  J Transl Med       Date:  2015-08-01       Impact factor: 5.531
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.