Literature DB >> 1167875

Localization of a thrombin-sensitive calcium pool in platelets.

T Sato, L Herman, J A Chandler, A Stracher, T C Detwiler.   

Abstract

Electron microscopic x-ray microprobe analysis of pyroantimonate precipitates in platelets fixed in osmium tetroxide-pyroantimonate revealed calcium localization in the nucleoids of alpha-granules. This pool of calcium had largely disappeared within 10 sec after stimulation of platelets by thrombin. Such a rapid change suggests that this calcium pool may have a regulatory role in stimulus-response coupling.

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Year:  1975        PMID: 1167875     DOI: 10.1177/23.2.1167875

Source DB:  PubMed          Journal:  J Histochem Cytochem        ISSN: 0022-1554            Impact factor:   2.479


  8 in total

1.  Ultrastructural localization of calcium around the membrane of the surface connected system in the human platelet.

Authors:  T Daimon; V Mizuhira; K Uchida
Journal:  Histochemistry       Date:  1978-05-16

2.  Cellular calcium distribution in fetal bones studied with K-pyroantimonate.

Authors:  E H Burger; J L Matthews
Journal:  Calcif Tissue Res       Date:  1978-12-08

3.  Platelet heterogeneity and dense tubular system changes on activation.

Authors:  R Yarom; G Lijovetzky; Y Havivi
Journal:  Experientia       Date:  1981-01-15

4.  Sodium and calcium localization in cells and tissues by precipitation with antimonate: a quantitative study.

Authors:  F Van Iren; L Van Essen-Joolen; P Van der Duyn Schouten; P Boers-Van der Sluijs; W C de Bruijn
Journal:  Histochemistry       Date:  1979-10

5.  Studies of platelets with heavy metal impregnation techniques.

Authors:  R Yarom; R More; Y Havivi; G Lijovetzky; S Meyer
Journal:  Histochem J       Date:  1982-01

6.  Cytochemical localization of lysosomal enzymes in rat megakaryocytes and platelets.

Authors:  M E Bentfeld; D F Bainton
Journal:  J Clin Invest       Date:  1975-12       Impact factor: 14.808

7.  Ultrastructural localization of acid protein polysaccharides and calcium in the vacuoles of the chicken thrombocyte.

Authors:  T Daimon; K Uchida; V Mizuhira
Journal:  Histochemistry       Date:  1977-04-20

8.  Pericellular Ca(2+) recycling potentiates thrombin-evoked Ca(2+) signals in human platelets.

Authors:  Stewart O Sage; Nicholas Pugh; Richard W Farndale; Alan G S Harper
Journal:  Physiol Rep       Date:  2013-10-11
  8 in total

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