Literature DB >> 11678671

Manoyl oxide alpha-arabinopyranoside and grindelic acid diterpenoids from Grindelia integrifolia.

A A Ahmed1, A A Mahmoud, U M Ahmed, A A El-Bassuony, M H Abd El-Razk, P W Pare, J Karchesy.   

Abstract

Two new manoyl oxide-alpha-arabinopyranoside diterpenoids, 15-hydroxy-13-epi-manoyl oxide-14-O-alpha-L-arabinopyranoside (tarapacol-14-O-alpha-L-arabinopyranoside) (1) and 15-acetoxy-13-epi-manoyl oxide-14-O-alpha-L-arabinopyranoside (tarapacol-15-acetate-14-O-alpha-L-arabinopyranoside) (2), as well as a new grindelic acid derivative, 19-hydroxygrindelic acid (3), together with five known diterpenoids (tarapacol, tarapacanol A, grindelic acid, methyl grindeloate, 3beta-hydroxygrindelic acid, 4) were isolated from the aerial parts of Grindelia integrifolia. The structures of 1-3 were elucidated by spectral data analysis.

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Year:  2001        PMID: 11678671     DOI: 10.1021/np010273n

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  2 in total

1.  Cativic acid-caffeic acid hybrid exerts cytotoxic effects and induces apoptotic death in human neuroblastoma cells.

Authors:  Natalia P Alza; Ana P Murray; Gabriela A Salvador
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2017-09-05       Impact factor: 3.000

Review 2.  Structural Diversity and Biological Activities of Diterpenoids Derived from Euphorbia fischeriana Steud.

Authors:  Baiyu Jian; Hao Zhang; Jicheng Liu
Journal:  Molecules       Date:  2018-04-18       Impact factor: 4.411

  2 in total

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