Literature DB >> 11678661

Cytotoxic cyclic norterpene peroxides from a Red Sea sponge Diacarnus erythraenus.

D T Youssef1, W Y Yoshida, M Kelly, P J Scheuer.   

Abstract

Investigation of the lipophilic extract of the Red Sea sponge Diacarnus erythraenus revealed one new norsesterterpene cyclic peroxide, aikupikoxide A (1), three new norditerpene cyclic peroxides, aikupikoxide B-D (2-4), and the known norterpene peroxides muqubilin and nuapapuin A methyl ester. In addition, a new sesquiterpene, O-methyl guaianediol, was isolated. Their structures were determined by means of spectroscopic methods. The cytotoxic activities for the isolated compounds have been reported.

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Year:  2001        PMID： 11678661     DOI： 10.1021/np010184a

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  8 in total

1.  Hypoxia-selective antitumor agents: norsesterterpene peroxides from the marine sponge Diacarnus levii preferentially suppress the growth of tumor cells under hypoxic conditions.

Authors:  Jingqiu Dai; Yang Liu; Yu-Dong Zhou; Dale G Nagle
Journal:  J Nat Prod       Date:  2007-01       Impact factor: 4.050

2.  Suppression of cyclooxygenase-2 and inducible nitric oxide synthase expression by epimuqubilin A via IKK/IκB/NF-κB pathways in lipopolysaccharide-stimulated RAW 264.7 cells.

Authors:  Eun-Jung Park; Sarot Cheenpracha; Leng Chee Chang; John M Pezzuto
Journal:  Phytochem Lett       Date:  2011-12-01       Impact factor: 1.679

3.  The marine sponge Diacarnus bismarckensis as a source of peroxiterpene inhibitors of Trypanosoma brucei, the causative agent of sleeping sickness.

Authors:  Brent K Rubio; Karen Tenney; Kean-Hooi Ang; Maha Abdulla; Michelle Arkin; James H McKerrow; Phillip Crews
Journal:  J Nat Prod       Date:  2009-02-27       Impact factor: 4.050

Review 4.  Molecular architecture and biomedical leads of terpenes from red sea marine invertebrates.

Authors:  Mohamed Elamir F Hegazy; Tarik A Mohamed; Montaser A Alhammady; Alaa M Shaheen; Eman H Reda; Abdelsamed I Elshamy; Mina Aziz; Paul W Paré
Journal:  Mar Drugs       Date:  2015-05-20       Impact factor: 5.118

5.  Relative and absolute stereochemistry of diacarperoxides: antimalarial norditerpene endoperoxides from marine sponge Diacarnus megaspinorhabdosa.

Authors:  Fan Yang; Yike Zou; Ru-Ping Wang; Mark T Hamann; Hong-Jun Zhang; Wei-Hua Jiao; Bing-Nan Han; Shao-Jiang Song; Hou-Wen Lin
Journal:  Mar Drugs       Date:  2014-08-08       Impact factor: 5.118

6.  In Search of Alternative Antibiotic Drugs: Quorum-Quenching Activity in Sponges and their Bacterial Isolates.

Authors:  Kumar Saurav; Rinat Bar-Shalom; Markus Haber; Ilia Burgsdorf; Giorgia Oliviero; Valeria Costantino; David Morgenstern; Laura Steindler
Journal:  Front Microbiol       Date:  2016-04-05       Impact factor: 5.640

Review 7.  Natural Products Repertoire of the Red Sea.

Authors:  Ebaa M El-Hossary; Mohammad Abdel-Halim; Eslam S Ibrahim; Sheila Marie Pimentel-Elardo; Justin R Nodwell; Heba Handoussa; Miada F Abdelwahab; Ulrike Holzgrabe; Usama Ramadan Abdelmohsen
Journal:  Mar Drugs       Date:  2020-09-04       Impact factor: 5.118

Review 8.  Marine Terpenic Endoperoxides.

Authors:  Irene Torres-García; Josefa L López-Martínez; Manuel Muñoz-Dorado; Ignacio Rodríguez-García; Miriam Álvarez-Corral
Journal:  Mar Drugs       Date:  2021-11-25       Impact factor: 5.118
  8 in total

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