| Literature DB >> 1167825 |
B M Ansell, D B Hanna, M Stoppard.
Abstract
A study was carried out in 9 children (mean age 10.8 years) suffering from rheumatic disorders to determine peak plasma levels and plasma curve of naproxen following the administration of a single oral dose of a suspension formulation. The results suggest that there is no significant difference in naproxen peak blood levels and half-life between adults and children and a twice-daily dosage regime, as in adults, should be suitable, therefore, for therapeutic use in children. The formulation was well-tolerated and no untoward effects were noted.Entities:
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Year: 1975 PMID: 1167825 DOI: 10.1185/03007997509113646
Source DB: PubMed Journal: Curr Med Res Opin ISSN: 0300-7995 Impact factor: 2.580