Literature DB >> 11677056

Dynamic temporal and spatial regulation of the cdk inhibitor p57(kip2) during embryo morphogenesis.

J Westbury1, M Watkins, A C Ferguson-Smith, J Smith.   

Abstract

The complete developmental expression pattern of the cyclin dependent kinase inhibitor (CDKI) p57(kip2) has not been reported, here we report a detailed study of the localization of p57(kip2) protein during mouse organogenesis. We show that p57(kip2) is coincident with key stages of differentiation of several organs, some but not all of which are affected in Beckwith-Weidermann syndrome, a human congenital syndrome characterized by foetal overgrowth and childhood tumours.

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Year:  2001        PMID： 11677056     DOI： 10.1016/s0925-4773(01)00512-3

Source DB:  PubMed          Journal:  Mech Dev        ISSN： 0925-4773            Impact factor:   1.882


  18 in total

1.  Adult and embryonic skeletal muscle microexplant culture and isolation of skeletal muscle stem cells.

Authors:  Deborah Merrick; Hung-Chih Chen; Dean Larner; Janet Smith
Journal:  J Vis Exp       Date:  2010-09-21       Impact factor: 1.355

Review 2.  The placental imprintome and imprinted gene function in the trophoblast glycogen cell lineage.

Authors:  Louis Lefebvre
Journal:  Reprod Biomed Online       Date:  2012-04-04       Impact factor: 3.828

3.  Knockdown of cyclin-dependent kinase inhibitors induces cardiomyocyte re-entry in the cell cycle.

Authors:  Valeria Di Stefano; Mauro Giacca; Maurizio C Capogrossi; Marco Crescenzi; Fabio Martelli
Journal:  J Biol Chem       Date:  2011-01-05       Impact factor: 5.157

4.  Checkpoint kinase 1 prevents cell cycle exit linked to terminal cell differentiation.

Authors:  Zakir Ullah; Christelle de Renty; Melvin L DePamphilis
Journal:  Mol Cell Biol       Date:  2011-07-26       Impact factor: 4.272

5.  A cell-autonomous requirement for Cip/Kip cyclin-kinase inhibitors in regulating neuronal cell cycle exit but not differentiation in the developing spinal cord.

Authors:  Hongxing Gui; Shike Li; Michael P Matise
Journal:  Dev Biol       Date:  2006-10-27       Impact factor: 3.582

6.  Fetal overgrowth in the Cdkn1c mouse model of Beckwith-Wiedemann syndrome.

Authors:  Simon J Tunster; Mathew Van de Pette; Rosalind M John
Journal:  Dis Model Mech       Date:  2011-07-04       Impact factor: 5.758

7.  ZAC, LIT1 (KCNQ1OT1) and p57KIP2 (CDKN1C) are in an imprinted gene network that may play a role in Beckwith-Wiedemann syndrome.

Authors:  Takahiro Arima; Tetsuya Kamikihara; Toshirou Hayashida; Kiyoko Kato; Toshiaki Inoue; Yasuaki Shirayoshi; Mitsuo Oshimura; Hidenobu Soejima; Tunehiro Mukai; Norio Wake
Journal:  Nucleic Acids Res       Date:  2005-05-11       Impact factor: 16.971

8.  Cip/Kip cyclin-dependent protein kinase inhibitors and the road to polyploidy.

Authors:  Zakir Ullah; Chrissie Y Lee; Melvin L Depamphilis
Journal:  Cell Div       Date:  2009-06-02       Impact factor: 5.130

9.  Forced expression of the cell cycle inhibitor p57Kip2 in cardiomyocytes attenuates ischemia-reperfusion injury in the mouse heart.

Authors:  Sheila A Haley; Ting Zhao; Lijun Zou; Jan E Klysik; James F Padbury; Lazaros K Kochilas
Journal:  BMC Physiol       Date:  2008-02-29

10.  A role for Insulin-like growth factor 2 in specification of the fast skeletal muscle fibre.

Authors:  Deborah Merrick; Tao Ting; Lukas Kurt Josef Stadler; Janet Smith
Journal:  BMC Dev Biol       Date:  2007-06-08       Impact factor: 1.978
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