Literature DB >> 11676621

Use of a new finger-mounted device to compare mechanical nociceptive thresholds in cats given pethidine or no medication after castration.

L S Slingsby1, A Jones, A E Waterman-Pearson.   

Abstract

Mechanical nociceptive thresholds are regularly used to determine the efficacy of analgesic agents both experimentally and clinically in a variety of species. The 'pressure of palpation device' (PPD) was developed for use in cats and is a small battery operated device with a finger-mounted force sensing resistor (FSR, Interlink Electronics, Northumberland. UK). The PPD was used in a study assessing the analgesic efficacy of pethidine after castration in cats. Pethidine was demonstrated to prevent the development of post-operative scrotal hypersensitivity for up to 2 hours after castration, whereas cats given no analgesics showed marked hyperalgesia immediately after surgery. Visual Analogue Scale (VAS) pain scores after castration showed a similar analgesic effect of pethidine. These results suggest that the PPD could become a useful research tool to assess the effectiveness of analgesic agents in the cat.

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Year:  2001        PMID: 11676621     DOI: 10.1053/rvsc.2001.0467

Source DB:  PubMed          Journal:  Res Vet Sci        ISSN: 0034-5288            Impact factor:   2.534


  4 in total

1.  Factors affecting mechanical (nociceptive) thresholds in piglets.

Authors:  Andrew M Janczak; Birgit Ranheim; Torunn K Fosse; Sophie Hild; Janicke Nordgreen; Randi O Moe; Adroaldo J Zanella
Journal:  Vet Anaesth Analg       Date:  2012-06-19       Impact factor: 1.648

2.  Influence of experimental protocol on response rate and repeatability of mechanical threshold testing in dogs.

Authors:  L K Harris; J C Murrell; E G M van Klink; H R Whay
Journal:  Vet J       Date:  2015-02-10       Impact factor: 2.688

Review 3.  Research Tools for the Measurement of Pain and Nociception.

Authors:  Craig Johnson
Journal:  Animals (Basel)       Date:  2016-11-11       Impact factor: 2.752

4.  Evaluation of oral robenacoxib for the treatment of postoperative pain and inflammation in cats: results of a randomized clinical trial.

Authors:  Stephen King; Elizabeth S Roberts; Linda M Roycroft; Jonathan N King
Journal:  ISRN Vet Sci       Date:  2012-07-01
  4 in total

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